Thin-layer chromatographic analysis of mangiferin (a bioactive antioxidant from dietary plant sources): a mini-review

The thin-layer chromatographic (TLC) analysis of extracts/compounds has several applications in the field of food, cosmetics, phytochemistry, and pharmaceutical industry. Mangiferin is a bioactive and natural antioxidant polyphenolic xanthone obtained from different dietary plants and recently gaining remarkable attention due to its high pharmacological significance evident in current scientific validations. This review contains various TLC methods reported so far for the qualitative and quantitative assessments of mangiferin after collating selected research papers from online scientific databases as PubMed, Web of Science, and Scopus. In particular, confirmation of mangiferin from dietary plant, herbal formulations, and biological and bioautographic samples through TLC are discussed in detail and comparison is also established in terms of selectivity, sensitivity, and validity. Ultimately, critical evaluation was done with the aim to deliver useful suggestions for the selection of suitable mobile phase, sample preparation, and detection methods for the analysis of mangiferin.