Interferon-induced paranoid psychosis: Review and case report [Interferoninduzierte paranoide psychose: Literaturübersicht und kasuistik]

Adverse neuropsychiatric effects under interferon treatment have often been reported. However, the pathogenetic mechanisms have not yet been fully explored. Most frequent are affective disorders, but psychotic decompensations can also occur, as reported in the following case. Thus, taking a detailed psychiatric history is required before starting a therapy with interferon, since past and current psychiatric disorders might imply an increased risk for psychiatric adverse effects.