Molecular screening of the proopiomelanocortin (POMC ) gene in Italian obese children: report of three new mutations

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作者
E Miraglia del Giudice
G Cirillo
N Santoro
L D'Urso
MT Carbone
R Di Toro
L Perrone
机构
[1] Second University of Naples,Department of Pediatrics
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关键词
proopiomelanocortin; signal peptide; obesity; leptin; children;
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摘要
BACKGROUND: Although linkage studies strongly suggest that proopiomelanocortin (POMC) alterations could play a role in the genetic predisposition to obesity, systematic POMC mutational analysis did not completely confirm this hypothesis.
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页码:61 / 67
页数:6
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