First trials test targeting of α-synuclein for Parkinson disease

被引：0

作者：

Lorraine V. Kalia

机构：

[1] University of Toronto,Division of Neurology, Department of Medicine

[2] Edmond J. Safra Program in Parkinson’s Disease and the Morton and Gloria Shulman Movement Disorders Clinic,Krembil Research Institute

[3] Toronto Western Hospital,undefined

[4] University Health Network,undefined

来源：

Nature Reviews Neurology | 2022年 / 18卷

关键词：

D O I：

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学科分类号：

摘要：

In the first two phase II trials of therapies that target α-synuclein to treat Parkinson disease, the primary endpoints were not met. However, the limitations of these studies need to be addressed in future trials and alternative approaches to targeting α-synuclein should be pursued before α-synuclein is discounted as a target.

引用

页码：703 / 704

页数：1

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