Tuft-cell-derived IL-25 regulates an intestinal ILC2–epithelial response circuit

被引：0
|
作者：
Jakob von Moltke
Ming Ji
Hong-Erh Liang
Richard M. Locksley
机构：
[1] University of California San Francisco,Department of Medicine
[2] Howard Hughes Medical Institute,Department of Microbiology & Immunology
[3] University of California San Francisco,undefined
[4] University of California San Francisco,undefined
来源：
Nature | 2016年 / 529卷
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学科分类号：
摘要：
Epithelial tuft cells are shown to be the source of intestinal interleukin (IL)-25 that is required for activation of type 2 innate lymphoid cells (ILC2s), ILC2-regulated tuft and goblet cell expansion, and control of parasite infection.
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页码：221 / 225
页数：4
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