A domino reaction for the synthesis of 2H-pyrano-[4″,3″,2″:4′,5′]chromeno[2′,3′:4,5]thieno-[2,3-b]pyridin-2-ones

被引：0

作者：

Svitlana P. Bondarenko

Igor V. Zhitnetskyi

Serhii V. Semenov

Mykhaylo S. Frasinyuk

机构：

[1] National University of Food Technologies,Institute of Bioorganic Chemistry and Petrochemistry

[2] National Academy of Sciences of Ukraine,undefined

来源：

Chemistry of Heterocyclic Compounds | 2016年 / 52卷

关键词：

4-chloromethylcoumarin; 4-(3-cyanopyridin-2-yl-sulfanylmethyl)coumarin; pyrano[4″,3″,2″:4′,5′]chromeno[2′,3′:4,5]thieno-[2,3-; ]pyridine; domino reaction; intramolecular cyclization;

D O I：

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学科分类号：

摘要：

[graphic not available: see fulltext] 2-{[(5-Hydroxy-2-oxo-2H-chromen-4-yl)methyl]sulfanyl}pyridine-3-carbonitrile derivatives were synthesized in a reaction of 4-chloromethyl-5-hydroxycoumarin with substituted 2-thioxopyridine-3-carbonitriles. The presence in the molecule of spatially adjacent active methylene, nitrile, and hydroxyl groups under the action of a base leads to consecutive intramolecular cyclization reactions with the formation of a novel heterocyclic system pyrano[4″,3″,2″:4′,5′]chromeno[2′,3′:4,5]thieno[2,3-b]pyridine.

引用

页码：262 / 266

页数：4

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[1] Erratum to: A Domino Reaction for the Synthesis of 2H-Pyrano-[4'',3'',2'':4',5']chromeno [2',3':4,5]thieno-[2,3-b]pyridin-2-ones
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Igor V. Zhytnetskyi
Serhii V. Semenov
Mykhaylo S. Frasinyuk
Chemistry of Heterocyclic Compounds, 2016, 52 : 352 - 352
[2] A Domino Reaction for the Synthesis of 2H-Pyrano-[4",3",2":4′,5′]chromeno [2′,3′:4,5]thieno-[2,3-b]pyridin-2-ones (vol 52, pg 262, 2016)
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