Iron-Dependent Synthesis of Hemolysins by Staphylococcus aureus

被引：0
|
作者：
V. V. Leonov
V. V. Kosterina
V. V. Varnitsina
T. Kh. Timokhina
N. A. Kurlovich
机构：
[1] Yugorsk State University,Department of Chemistry
[2] Tyumen’ State Medical Academy,Department of Microbiology
来源：
Bulletin of Experimental Biology and Medicine | 2012年 / 153卷
关键词：
iron; hemolytic activity; hemolysins;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
We studied the effect of Fe2+ on hemolysin synthesis by Staphylococcus aureus. Hemolytic activity of staphylococci was shown to be iron-dependent. Addition of Fe2+ to the nutrient medium induced the synthesis of α-hemolysin by staphylococci. Increasing the concentration of Fe2+ was followed by an increase in hemolytic activity of staphylococci. Inducible synthesis of α-hemolysin probably serves as an important pathogenetic factor in the development of staphylococcal infection in patients with excessive iron accumulation in the body.
引用
收藏
页码：41 / 43
页数：2
相关论文
共 50 条
  • [1] Iron-Dependent Synthesis of Hemolysins by Staphylococcus aureus
    Leonov, V. V.
    Kosterina, V. V.
    Varnitsina, V. V.
    Timokhina, T. Kh.
    Kurlovich, N. A.
    BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE, 2012, 153 (01) : 41 - 43
  • [2] HEMOLYSINS OF STAPHYLOCOCCUS-AUREUS
    WISEMAN, GM
    BACTERIOLOGICAL REVIEWS, 1975, 39 (04) : 317 - 344
  • [3] Lipoproteins in Staphylococcus aureus Mediate Inflammation by TLR2 and Iron-Dependent Growth In Vivo
    Schmaler, Mathias
    Jann, Naja J.
    Ferracin, Fabrizia
    Landolt, Lea Z.
    Biswas, Lalitha
    Goetz, Friedrich
    Landmann, Regine
    JOURNAL OF IMMUNOLOGY, 2009, 182 (11): : 7110 - 7118
  • [4] SirR, a novel iron-dependent repressor in Staphylococcus epidermidis
    Hill, PJ
    Cockayne, A
    Landers, P
    Morrissey, JA
    Sims, CM
    Williams, P
    INFECTION AND IMMUNITY, 1998, 66 (09) : 4123 - 4129
  • [5] HEMOLYSINS OF STAPHYLOCOCCUS-AUREUS AND THEIR SIGNIFICANCE IN TYPING
    ELIAS, B
    KOFER, J
    MAGYAR ALLATORVOSOK LAPJA, 1980, 35 (05) : 342 - 346
  • [6] STAPHYLOCOCCUS-AUREUS HEMOLYSINS - THEIR USE IN STRAIN TYPING
    ELIAS, B
    KOFER, J
    ACTA MICROBIOLOGICA ACADEMIAE SCIENTIARUM HUNGARICAE, 1980, 27 (03): : 183 - 190
  • [7] A RAPID METHOD FOR THE DIFFERENTIATION OF STAPHYLOCOCCUS-AUREUS HEMOLYSINS
    RUZICKOVA, V
    FOLIA MICROBIOLOGICA, 1994, 39 (02) : 112 - 114
  • [8] IRON-DEPENDENT UREIDES AND ALLANTIONASE SYNTHESIS IN PIGEON PEA
    REDDY, DS
    REDDY, G
    POLASA, H
    JOURNAL OF PLANT NUTRITION, 1995, 18 (05) : 937 - 947
  • [9] REGULATION OF ALPHA-HEMOLYSINS AND BETA-HEMOLYSINS BY THE SAR LOCUS OF STAPHYLOCOCCUS-AUREUS
    CHEUNG, AL
    YING, P
    JOURNAL OF BACTERIOLOGY, 1994, 176 (03) : 580 - 585
  • [10] The mode of action of bicomponent gamma-hemolysins of Staphylococcus aureus
    不详
    EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS, 2005, 34 (06): : 755 - 755
12345