The Chemical Composition and Biological Activities of Essential Oil from the Leaves of Philadelphus x purpureomaculatus Lemoine

被引：0
|
作者：
Farukh Sharopov
Prabodh Satyal
Michael Wink
机构：
[1] Heidelberg University,Institute of Pharmacy and Molecular Biotechnology
[2] Avicenna Tajik State Medical University,Department of Pharmaceutical Technology
[3] University of Alabama in Huntsville,Department of Chemistry
来源：
Pharmaceutical Chemistry Journal | 2020年 / 54卷
关键词：
Lemoine; essential oil; terpenoids; viridiflorol;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
The essential oil from the leaves of Philadelphus x purpureomaculatus Lemoine was obtained by hydrodistillation and analyzed by high-resolution gas-liquid chromatography - mass spectrometry (GLC-MS). The essential oil of P. x purpureomaculatus leaves was dominated by terpenoids containing hydroxyl and carbonyl groups. The major components of P. x purpureomaculatus essential oil were viridiflorol (44.4%), manool (31.2%), pentadecanal (5.4%), and borneol (4.9%). Antioxidant capacity and cytotoxicity of methanol extracts and essential oil of P. x purpureomaculatus were evaluated by using DPPH-, ABTS-, FRAP- and MTTassays. Extracts from P. x purpureomaculatus have shown weak antioxidant activity compare with positive control (caffeic acid). The highest cytotoxicity effect was observed with methanol leave extract on CCRF-CEM cells with IC50 value 38.5 μg/ml.
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页码：386 / 388
页数：2
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