Dynamic membrane transformations are not exclusively controlled by cytoskeletal rearrangement, but also by biophysical constraints, adhesive forces, membrane curvature and compaction. Recent technological advances have helped clarify longstanding controversies concerning myelination, from target selection to axon wrapping and membrane compaction. Chang et al. review these findings and discuss how understanding these processes provides insight into myelination-centered mechanisms of neural plasticity.
机构:
Univ Calif San Francisco, Dept Neurol, San Francisco, CA USAUniv Calif San Francisco, Dept Neurol, San Francisco, CA USA
Chang, Kae-Jiun
Redmond, Stephanie A.
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机构:
Univ Calif San Francisco, Dept Neurol, San Francisco, CA USA
Univ Calif San Francisco, Program Neurosci, San Francisco, CA 94143 USAUniv Calif San Francisco, Dept Neurol, San Francisco, CA USA
Redmond, Stephanie A.
Chan, Jonah R.
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h-index: 0
机构:
Univ Calif San Francisco, Dept Neurol, San Francisco, CA USA
Univ Calif San Francisco, Program Neurosci, San Francisco, CA 94143 USAUniv Calif San Francisco, Dept Neurol, San Francisco, CA USA