Tanshinone I exerts cardiovascular protective effects in vivo and in vitro through inhibiting necroptosis via Akt/Nrf2 signaling pathway

被引：0
|
作者：
Youqiong Zhuo
Renyikun Yuan
Xinxin Chen
Jia He
Yangling Chen
Chenwei Zhang
Kaili Sun
Shilin Yang
Zhenjie Liu
Hongwei Gao
机构：
[1] Guangxi University of Chinese Medicine,College of Pharmacy
[2] Guangxi Engineering Technology Research Center of Advantage Chinese Patent Drug and Ethnic Drug Development,State Key Laboratory of Innovative Drug and Efficient Energy
[3] Jiangxi University of Traditional Chinese Medicine,Saving Pharmaceutical Equipment
来源：
Chinese Medicine | / 16卷
关键词：
Tanshinone I; Oxidative stress; Necroptosis; Myocardial ischemia reperfusion; RIP1/RIP3/MLKL; Akt/Nrf2;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
相关论文
共 50 条
  • [1] Tanshinone I exerts cardiovascular protective effects in vivo and in vitro through inhibiting necroptosis via Akt/Nrf2 signaling pathway
    Zhuo, Youqiong
    Yuan, Renyikun
    Chen, Xinxin
    He, Jia
    Chen, Yangling
    Zhang, Chenwei
    Sun, Kaili
    Yang, Shilin
    Liu, Zhenjie
    Gao, Hongwei
    CHINESE MEDICINE, 2021, 16 (01)
  • [2] Pomiferin Exerts Antineuroinflammatory Effects through Activating Akt/Nrf2 Pathway and Inhibiting NF-κB Pathway
    Zhao, Yan
    Sang, Yuxuan
    Sun, Yanan
    Wu, Jie
    MEDIATORS OF INFLAMMATION, 2022, 2022
  • [3] Imperatorin exerts antioxidant effects in vascular dementia via the Nrf2 signaling pathway
    Xiangping Liao
    Ziliang Zhang
    Min Ming
    Shanquan Zhong
    Jianping Chen
    Ying Huang
    Scientific Reports, 13
  • [4] Imperatorin exerts antioxidant effects in vascular dementia via the Nrf2 signaling pathway
    Liao, Xiangping
    Zhang, Ziliang
    Ming, Min
    Zhong, Shanquan
    Chen, Jianping
    Huang, Ying
    SCIENTIFIC REPORTS, 2023, 13 (01)
  • [5] Scutellarin Exerts Hypoglycemic and Renal Protective Effects in db/db Mice via the Nrf2/HO-1 Signaling Pathway
    Liu, Yange
    Wang, Juan
    Zhang, Xinrui
    Wang, Li
    Hao, Tian
    Cheng, Yanli
    Wang, Di
    OXIDATIVE MEDICINE AND CELLULAR LONGEVITY, 2019, 2019
  • [6] Camptothecin Regulates Microglia Polarization and Exerts Neuroprotective Effects via Activating AKT/Nrf2/HO-1 and Inhibiting NF-κB Pathways In Vivo and In Vitro
    He, Dewei
    Fu, Shoupeng
    Zhou, Ang
    Su, Yingchun
    Gao, Xiyu
    Zhang, Yufei
    Huang, Bingxu
    Du, Jian
    Liu, Dianfeng
    FRONTIERS IN IMMUNOLOGY, 2021, 12
  • [7] Tanshinone I inhibits doxorubicin-induced cardiotoxicity by regulating Nrf2 signaling pathway
    Jiang, Qianqian
    Chen, Xu
    Tian, Xue
    Zhang, Jingmei
    Xue, Siming
    Jiang, Yanyan
    Liu, Tiantian
    Wang, Xiaoping
    Sun, Qianbin
    Hong, Yiqin
    Li, Chun
    Guo, Dongqing
    Wang, Yong
    Wang, Qiyan
    PHYTOMEDICINE, 2022, 106
  • [8] Curcumin Improves Diabetic Cardiomyopathy by Inhibiting Pyroptosis through AKT/Nrf2/ARE Pathway
    Wei, Zhang
    Pinfang, Kang
    Jing, Zhou
    Zhuoya, Yao
    Shaohuan, Qian
    Chao, Shi
    MEDIATORS OF INFLAMMATION, 2023, 2023
  • [9] Sanbai Melon Seed Oil Exerts Its Protective Effects in a Diabetes Mellitus Model via the Akt/GSK-3β/Nrf2 Pathway
    Wang, Fang
    Xi, Yuanhang
    Liu, Wenzhe
    Li, Jie
    Zhang, Ya
    Jia, Min
    He, Qiaoyan
    Zhao, Hongsheng
    Wang, Siwang
    JOURNAL OF DIABETES RESEARCH, 2019, 2019
  • [10] Ethanol Extract of Centipeda minima Exerts Antioxidant and Neuroprotective Effects via Activation of the Nrf2 Signaling Pathway
    Wang, Yi-Jie
    Wang, Xin-Yue
    Hao, Xu-Yi
    Yan, Yong-Ming
    Hong, Ming
    Wei, Su-Fen
    Zhou, Yi-Le
    Wang, Qi
    Cheng, Yong-Xian
    Liu, Yong-Qiang
    OXIDATIVE MEDICINE AND CELLULAR LONGEVITY, 2019, 2019
12345