Mefenamic Acid Loaded and TPGS Stabilized Mucoadhesive Nanoemulsion for the Treatment of Alzheimer’s Disease: Development, Optimization, and Brain-Targeted Delivery via Olfactory Pathway

被引:0
|
作者
Anmol Dogra
Ramandeep Singh Narang
Tajpreet Kaur
Jasjeet Kaur Narang
机构
[1] I.K.G Punjab Technical University,Department of Pharmaceutics
[2] Khalsa College of Pharmacy,Department of Oral and Maxillofacial Pathology
[3] Sri Guru Ram Das Institute of Dental Sciences and Research,Department of Pharmacology
[4] Khalsa College of Pharmacy,undefined
来源
关键词
Alzheimer’s disease; cell line toxicity study; mucoadhesive nanoemulsion; pharmacodynamics study; stability study;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
相关论文
共 8 条
  • [1] Mefenamic Acid Loaded and TPGS Stabilized Mucoadhesive Nanoemulsion for the Treatment of Alzheimer's Disease: Development, Optimization, and Brain-Targeted Delivery via Olfactory Pathway
    Dogra, Anmol
    Narang, Ramandeep Singh
    Kaur, Tajpreet
    Narang, Jasjeet Kaur
    [J]. AAPS PHARMSCITECH, 2024, 25 (01)
  • [2] Osthole-Loaded Nanoemulsion Enhances Brain Target in the Treatment of Alzheimer's Disease via Intranasal Administration
    Song, Yilei
    Wang, Xiangyu
    Wang, Xingrong
    Wang, Jianze
    Hao, Qiulian
    Hao, Jifu
    Hou, Xueqin
    [J]. OXIDATIVE MEDICINE AND CELLULAR LONGEVITY, 2021, 2021
  • [3] Intranasal Piperine-Loaded Chitosan Nanoparticles as Brain-Targeted Therapy in Alzheimer's Disease: Optimization, Biological Efficacy, and Potential Toxicity
    Elnaggar, Yosra S. R.
    Etman, Samar M.
    Abdelmonsif, Doaa A.
    Abdallah, Ossama Y.
    [J]. JOURNAL OF PHARMACEUTICAL SCIENCES, 2015, 104 (10) : 3544 - 3556
  • [4] A Brain-Targeted Approach to Ameliorate Memory Disorders in a Sporadic Alzheimer's Disease Mouse Model via Intranasal Luteolin-Loaded Nanobilosomes
    Elsheikh, Manal A.
    El-Feky, Yasmin A.
    Al-Sawahli, Majid Mohammad
    Ali, Merhan E.
    Fayez, Ahmed M.
    Abbas, Haidy
    [J]. PHARMACEUTICS, 2022, 14 (03)
  • [5] Intranasal delivery of tetrabenazine nanoemulsion via olfactory region for better treatment of hyperkinetic movement associated with Huntington's disease: Pharmacokinetic and brain delivery study
    Arora, Anmol
    Kumar, Shobhit
    Ali, Javed
    Baboota, Sanjula
    [J]. CHEMISTRY AND PHYSICS OF LIPIDS, 2020, 230
  • [6] Targeted brain delivery of RVG29-modified rifampicin-loaded nanoparticles for Alzheimer's disease treatment and diagnosis
    Zhou, Ruiyi
    Zhu, Lihong
    Zeng, Zhaohao
    Luo, Rixin
    Zhang, Jiawei
    Guo, Rui
    Zhang, Lei
    Zhang, Qunying
    Bi, Wei
    [J]. BIOENGINEERING & TRANSLATIONAL MEDICINE, 2022, 7 (03)
  • [7] Brain-targeted co-delivery of β-amyloid converting enzyme 1shRNAand epigallocatechin-3-gallate by multifunctional nanocarriers for Alzheimer's disease treatment
    Lv, Lijie
    Yang, Fan
    Li, He
    Yuan, Jiuli
    [J]. IUBMB LIFE, 2020, 72 (08) : 1819 - 1829
  • [8] Nose-to-Brain Targeted Delivery of Donepezil Hydrochloride via Novel Hyaluronic Acid-Doped Nanotransfersomes for Alzheimer's Disease Mitigation
    Salem, Heba F.
    Aboud, Heba M.
    Abdellatif, Mostafa M.
    Abou-Taleb, Heba A.
    [J]. JOURNAL OF PHARMACEUTICAL SCIENCES, 2024, 113 (07) : 1934 - 1945