Panobinostat reduces hypoxia-induced cisplatin resistance of non-small cell lung carcinoma cells via HIF-1α destabilization

被引：0
|
作者：
Carina Fischer
Katharina Leithner
Christoph Wohlkoenig
Franz Quehenberger
Alexandra Bertsch
Andrea Olschewski
Horst Olschewski
Andelko Hrzenjak
机构：
[1] Medical University of Graz,Division of Pulmonology, Department of Internal Medicine
[2] Red Cross Transfusion Service for Upper Austria,Institute of Medical Informatics, Statistics and Documentation
[3] Medical University of Graz,Ludwig Boltzmann Institute for Lung Vascular Research
[4] Medical University of Graz,undefined
来源：
Molecular Cancer | / 14卷
关键词：
Non-small cell lung cancer; Cisplatin; Panobinostat; Apoptosis; HIF-1α;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
相关论文
共 50 条
  • [1] Panobinostat reduces hypoxia-induced cisplatin resistance of non-small cell lung carcinoma cells via HIF-1α destabilization
    Fischer, Carina
    Leithner, Katharina
    Wohlkoenig, Christoph
    Quehenberger, Franz
    Bertsch, Alexandra
    Olschewski, Andrea
    Olschewski, Horst
    Hrzenjak, Andelko
    MOLECULAR CANCER, 2015, 14
  • [2] Histone deacetylase inhibitor panobinostat reduces hypoxia-induced cisplatin resistance of non-small cell lung carcinoma cells via HIF-1α destabilization
    Fischer, C.
    Leithner, K.
    Wohlkoenig, C.
    Quehenberger, F.
    Bertsch, A.
    Olschewski, A.
    Olschewski, H.
    Hrzenjak, A.
    WIENER KLINISCHE WOCHENSCHRIFT, 2015, 127 (19-20) : 816 - 817
  • [3] Panobinostat reduces hypoxia-related cisplatin resistance of non-small cell lung carcinoma cells via HIF-1alpha destabilization
    Hrzenjak, A.
    Fischer, C.
    Leithner, K.
    Wohlkoenig, C.
    Quehenberger, F.
    Olschewski, A.
    Olschewski, H.
    EUROPEAN JOURNAL OF CANCER, 2014, 50 : S203 - S204
  • [4] Hypoxia-induced resistance to cisplatin and doxorubicin in non-small cell lung cancer is inhibited by silencing of HIF-1α gene
    Xianrang Song
    Xianxi Liu
    Weiling Chi
    Yonglei Liu
    Ling Wei
    Xingwu Wang
    Jinming Yu
    Cancer Chemotherapy and Pharmacology, 2006, 58 : 776 - 784
  • [5] Hypoxia-induced resistance to cisplatin and doxorubicin in non-small cell lung cancer is inhibited by silencing of HIF-1α gene
    Song, Xianrang
    Liu, Xianxi
    Chi, Weiling
    Liu, Yonglei
    Wei, Ling
    Wang, Xingwu
    Yu, Jinming
    CANCER CHEMOTHERAPY AND PHARMACOLOGY, 2006, 58 (06) : 776 - 784
  • [6] Hypoxia-induced Tie1 drives stemness and cisplatin resistance in non-small cell lung carcinoma cells
    Chaojie Li
    Nannan Yang
    Zhijin Chen
    Ning Xia
    Qungang Shan
    Ziyin Wang
    Jian Lu
    Mingyi Shang
    Zhongmin Wang
    Cancer Cell International, 21
  • [7] Hypoxia-induced Tie1 drives stemness and cisplatin resistance in non-small cell lung carcinoma cells
    Li, Chaojie
    Yang, Nannan
    Chen, Zhijin
    Xia, Ning
    Shan, Qungang
    Wang, Ziyin
    Lu, Jian
    Shang, Mingyi
    Wang, Zhongmin
    CANCER CELL INTERNATIONAL, 2021, 21 (01)
  • [8] KLF5 promotes hypoxia-induced survival and inhibits apoptosis in non-small cell lung cancer cells via HIF-1α
    Li, Xiaochen
    Liu, Xiansheng
    Xu, Yongjian
    Liu, Jin
    Xie, Min
    Ni, Wang
    Chen, Shixin
    INTERNATIONAL JOURNAL OF ONCOLOGY, 2014, 45 (04) : 1507 - 1514
  • [9] Hypoxia-Induced Cisplatin Resistance in Non-Small Cell Lung Cancer Cells Is Mediated by HIF-1α and Mutant p53 and Can Be Overcome by Induction of Oxidative Stress
    Deben, Christophe
    Deschoolmeester, Vanessa
    De Waele, Jorrit
    Jacobs, Julie
    Van den Bossche, Jolien
    Wouters, An
    Peeters, Marc
    Rolfo, Christian
    Smits, Evelien
    Lardon, Filip
    Pauwels, Patrick
    CANCERS, 2018, 10 (04)
  • [10] Hypoxia-inducible factor 1 (HIF-1) expression in non-small cell lung carcinoma
    Krochmal, JD
    Dearmond, D
    Kernstine, K
    DeYoung, BR
    MODERN PATHOLOGY, 2005, 18 : 313A - 314A
12345