Methyl 3,3,3-trifluoro-2-diazopropionate for the synthesis of functionalized styrenes

被引：0
|
作者：
D. V. Vorobyeva
I. E. Yagafarova
T. P. Vasilyeva
S. N. Osipov
机构：
[1] Russian Academy of Sciences,A. N. Nesmeyanov Institute of Organoelement Compounds
来源：
Russian Chemical Bulletin | 2016年 / 65卷
关键词：
diazocompound; carbene; phenol; aniline; fluoro-containing styrenes;
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学科分类号：
摘要：
The efficient method for the synthesis of novel trifluoromethyl-containing hydroxy- and aminostyrenes has been developed. The reaction sequence includes the selective insertion of CF3-substituted carbene, which was catalytically derived from methyl 3,3,3-trifluoro-2-diazopropionate, into the OH- or NH-bonds of easily available o-bromophenol and o-bromoaniline derivatives followed by a bromine substitution for vinyl group via Pd-catalyzed Stille reaction.
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页码：2668 / 2671
页数：3
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