Lack of generalisation between the GABAA receptor agonist, gaboxadol, and allosteric modulators of the benzodiazepine binding site in the rat drug discrimination procedure

被引：0

作者：

Signe Michelsen

Connie Sánchez

Bjarke Ebert

机构：

[1] H. Lundbeck A/S,Department of Neuropharmacology

[2] Lundbeck Research USA,Neuroscience

[3] H. Lundbeck A/S,Department of Electrophysiology

来源：

Psychopharmacology | 2007年 / 193卷

关键词：

Drug discrimination; Gaboxadol; Diazepam; Zolpidem; Indiplon GABA; receptor; Rat;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

引用

页码：151 / 157

页数：6

共 20 条

[1] Lack of generalisation between the GABAA receptor agonist, gaboxadol, and allosteric modulators of the benzodiazepine binding site in the rat drug discrimination procedure
Sanchez, C.
Ebert, B.
SLEEP, 2006, 29 : A243 - A244
[2] Lack of generalisation between the GABAA receptor agonist, gaboxadol, and allosteric modulators of the benzodiazepine binding site in the rat drug discrimination procedure
Michelsen, Signe
Sanchez, Connie
Ebert, Bjarke
PSYCHOPHARMACOLOGY, 2007, 193 (01) : 151 - 157
[3] Rotarod studies in the rat of the GABAA receptor agonist gaboxadol:: lack of ethanol potentiation and benzodiazepine cross-tolerance
Voss, J
Sanchez, C
Michelsen, S
Ebert, B
EUROPEAN JOURNAL OF PHARMACOLOGY, 2003, 482 (1-3) : 215 - 222
[4] Structural Link between γ-Aminobutyric Acid Type A (GABAA) Receptor Agonist Binding Site and Inner β-Sheet Governs Channel Activation and Allosteric Drug Modulation
Venkatachalan, Srinivasan P.
Czajkowski, Cynthia
JOURNAL OF BIOLOGICAL CHEMISTRY, 2012, 287 (09) : 6714 - 6724
[5] Gaboxadol, a selective extrasynaptic GABAA agonist, does not generalise to other sleep-enhancing drugs:: A rat drug discrimination study
McDonald, L. M.
Sheppard, W. F.
Staveley, S. M.
Sohal, B.
Tattersall, F. D.
Hutson, P. H.
NEUROPHARMACOLOGY, 2007, 52 (03) : 844 - 853
[6] Acute pentylenetetrazol injection reduces rat GABAA receptor mRNA levels and GABA stimulation of benzodiazepine binding with no effect on benzodiazepine binding site density
Walsh, LA
Li, M
Zhao, TJ
Chiu, TH
Rosenberg, HC
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 1999, 289 (03): : 1626 - 1633
[7] The antiepileptic drug AWD 131-138 stimulates different recombinant isoforms of the rat GABAA receptor through the benzodiazepine binding site
Sigel, E
Baur, R
Netzer, R
Rundfeldt, C
NEUROSCIENCE LETTERS, 1998, 245 (02) : 85 - 88
[8] Pharmacology of the β-carboline FG-7142, a partial inverse agonist at the benzodiazepine allosteric site of the GABAA receptor:: Neurochemical, neurophysiological, and behavioral effects
Evans, Andrew K.
Lowry, Christopher A.
CNS DRUG REVIEWS, 2007, 13 (04): : 475 - 501
[9] Overlapping Binding Site for the Endogenous Agonist, Small-Molecule Agonists, and Ago-allosteric Modulators on the Ghrelin Receptor
Holst, Birgitte
Frimurer, Thomas M.
Mokrosinski, Jacek
Halkjaer, Tine
Cullberg, Karina B.
Underwood, Christina R.
Schwartz, Thue W.
MOLECULAR PHARMACOLOGY, 2009, 75 (01) : 44 - 59
[10] Structure-activity relationships and molecular modeling analysis of flavonoids binding to the benzodiazepine site of the rat brain GABAA receptor complex
Dekermendjian, K
Kahnberg, P
Witt, MR
Sterner, O
Nielsen, M
Liljefors, T
JOURNAL OF MEDICINAL CHEMISTRY, 1999, 42 (21) : 4343 - 4350

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