2,4-diamino-6-(acetohydrazidomethylsulfinylmethyl)-1,3,5-triazine. State in solution, acid-base and complexing properties

被引：0

作者：

V. V. Neklyudov

G. A. Boos

S. G. Fattakhov

G. A. Chmutova

M. M. Shulaeva

Yu. I. Salnikov

机构：

[1] Kazanskii (Volga) Federal University,Arbuzov Institute of Organic and Physical Chemistry, Kazan Scientific Center

[2] Russian Academy of Sciences,undefined

来源：

Russian Journal of General Chemistry | 2013年 / 83卷

关键词：

General Chemistry; Triazine; Hydrazide; Acid Hydrazide; Amide Form;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

Solutions of a new drug, 2,4-diamino-6-(acetylhydrazidomethylsulfonylmethyl)-1,3,5-triazine, exhibiting tuberculocidal activity were studied using the methods of pH-metry, spectrophotometry, mathematical simulation of equilibria (CPESSP software), and molecular mechanics. Protolytic properties of the compound in the medium of aqueous dimethylsulfoxide (40 vol % of DMSO) were characterized. The composition of the copper(II) complex of this compound was determined and its stability constants were calculated. Based on the absorption spectra in the UV and visible regions the complexing ability of 2,4-diamino-6-(acetylhydrazidomethylsulfonylmethyl)-1,3,5-triazine toward nickel(II) and cobalt(II) were characterized in comparison with copper(II) under the same conditions.

引用

页码：1369 / 1375

页数：6

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