Foxn1 regulates key target genes essential for T cell development in postnatal thymic epithelial cells

被引：0
|
作者：
Saulius Žuklys
Adam Handel
Saule Zhanybekova
Fatima Govani
Marcel Keller
Stefano Maio
Carlos E Mayer
Hong Ying Teh
Katrin Hafen
Giuseppe Gallone
Thomas Barthlott
Chris P Ponting
Georg A Holländer
机构：
[1] University Children's Hospital and University of Basel,Department of Biomedicine
[2] MRC Functional Genomics Unit,Department of Physiology
[3] Anatomy and Genetics,Department of Paediatrics and the Weatherall Institute of Molecular Medicine
[4] University of Oxford,undefined
[5] University of Oxford,undefined
[6] Present addresses: Department of Chemistry,undefined
[7] University of Basel,undefined
[8] Basel,undefined
[9] Switzerland (S. Zhanybekova),undefined
[10] Actelion Pharmaceuticals Ltd,undefined
[11] Allschwil,undefined
[12] Switzerland (M.K.),undefined
[13] MRC Institute of Genetics and Molecular Medicine,undefined
[14] University of Edinburgh,undefined
[15] Edinburgh,undefined
[16] UK (C.P.P.).,undefined
来源：
Nature Immunology | 2016年 / 17卷
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摘要：
Holländer and colleagues provide a map of genes that are direct targets of the transcription factor Foxn1 in thymic epithelial cells and show that Foxn1 controls genes encoding products involved in thymocyte development, antigen processing and thymocyte selection.
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页码：1206 / 1215
页数：9
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