Nerve growth factor novel dipeptide mimetic GK-2 selectively activates TrkA postreceptor signaling pathways and does not cause adverse effects of native neurotrophin

被引:0
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作者
T. A. Gudasheva
T. A. Antipova
M. A. Konstantinopolsky
P. Yu. Povarnina
S. B. Seredenin
机构
[1] Russian Academy of Medical Sciences,Zakusov Research Institute of Pharmacology
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关键词
Nerve Growth Factor; Pain Threshold; DOKLADY Biochemistry; TrkA Receptor; Hippocampal Neuron Culture;
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页码:88 / 91
页数:3
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  • [1] Nerve growth factor novel dipeptide mimetic GK-2 selectively activates TrkA postreceptor signaling pathways and does not cause adverse effects of native neurotrophin
    Gudasheva, T. A.
    Antipova, T. A.
    Konstantinopolsky, M. A.
    Povarnina, P. Yu.
    Seredenin, S. B.
    [J]. DOKLADY BIOCHEMISTRY AND BIOPHYSICS, 2014, 456 (01) : 88 - 91
  • [2] Antiparkinsonian Properties of a Nerve Growth Factor Dipeptide Mimetic GK-2 in in Vivo Experiments
    Povarnina, P. Yu.
    Gudasheva, T. A.
    Vorontsova, O. N.
    Bondarenko, N. A.
    Seredenin, S. B.
    [J]. BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE, 2011, 151 (06) : 690 - 693
  • [3] Antiparkinsonian Properties of a Nerve Growth Factor Dipeptide Mimetic GK-2 in in Vivo Experiments
    P. Yu. Povarnina
    T. A. Gudasheva
    O. N. Vorontsova
    N. A. Bondarenko
    S. B. Seredenin
    [J]. Bulletin of Experimental Biology and Medicine, 2011, 151 : 690 - 693
  • [4] Synthesis of GK-2, a Dimeric Dipeptide Nerve Growth Factor Mimetic and Potential Neuroprotective Agent
    Sazonova, N. M.
    Tarasyuk, A. V.
    Kurilov, D. V.
    Pomogaibo, S. V.
    Gudasheva, T. A.
    [J]. PHARMACEUTICAL CHEMISTRY JOURNAL, 2015, 49 (07) : 439 - 448
  • [5] Synthesis of GK-2, a Dimeric Dipeptide Nerve Growth Factor Mimetic and Potential Neuroprotective Agent
    N. M. Sazonova
    A. V. Tarasyuk
    D. V. Kurilov
    S. V. Pomogaibo
    T. A. Gudasheva
    [J]. Pharmaceutical Chemistry Journal, 2015, 49 : 439 - 448
  • [6] Evidence of Selective Interaction of Nerve Growth Factor Dipeptide Mimetic GK-2 with TrkA Receptor Using TrkA and TrkB Knockout HT-22 Cells
    Antipova, T. A.
    Deev, I. E.
    Gudasheva, T. A.
    Nikolaev, S. V.
    Logvinov, I. O.
    Serova, O. V.
    Gavrilenkova, A. A.
    Povarnina, P. Yu.
    Tarasiuk, A. V.
    Vakhitova, Yu. V.
    Seredenin, S. B.
    [J]. PHARMACEUTICAL CHEMISTRY JOURNAL, 2023, 56 (12) : 1568 - 1572
  • [7] Evidence of Selective Interaction of Nerve Growth Factor Dipeptide Mimetic GK-2 with TrkA Receptor Using TrkA and TrkB Knockout HT-22 Cells
    T. A. Antipova
    I. E. Deev
    T. A. Gudasheva
    S. V. Nikolaev
    I. O. Logvinov
    O. V. Serova
    A. A. Gavrilenkova
    P. Yu. Povarnina
    A. V. Tarasiuk
    Yu. V. Vakhitova
    S. B. Seredenin
    [J]. Pharmaceutical Chemistry Journal, 2023, 56 : 1568 - 1572
  • [8] Original Nerve Growth Factor Mimetic Dipeptide GK-2 Limits the Manifestations of Hemorrhagic Stroke in Rats
    V. A. Kraineva
    T. A. Gudasheva
    S. O. Kotelnikova
    T. A. Antipova
    S. B. Seredenin
    [J]. Bulletin of Experimental Biology and Medicine, 2013, 154 : 642 - 644
  • [9] Original Nerve Growth Factor Mimetic Dipeptide GK-2 Limits the Manifestations of Hemorrhagic Stroke in Rats
    Kraineva, V. A.
    Gudasheva, T. A.
    Kotelnikova, S. O.
    Antipova, T. A.
    Seredenin, S. B.
    [J]. BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE, 2013, 154 (05) : 642 - 644
  • [10] Synthesis and In Vitro Neuroprotector Activity of Diastereoisomers of a Dimeric Dipeptide Mimetic of Nerve Growth Factor GK-2
    N. M. Sazonova
    A. V. Tarasyuk
    A. N. Shumskii
    A. G. Rebeko
    P. I. Antipov
    I. O. Logvinov
    T. A. Antipova
    T. A. Gudasheva
    [J]. Pharmaceutical Chemistry Journal, 2018, 52 : 704 - 710