Comparative oncology reveals DNMT3B as a molecular vulnerability in undifferentiated pleomorphic sarcoma

被引:0
|
作者
Ashley M. Fuller
Ann DeVine
Ileana Murazzi
Nicola J. Mason
Kristy Weber
T. S. Karin Eisinger-Mathason
机构
[1] Abramson Family Cancer Research Institute,
[2] Department of Pathology and Laboratory Medicine,undefined
[3] Penn Sarcoma Program,undefined
[4] Perelman School of Medicine,undefined
[5] University of Pennsylvania,undefined
[6] Department of Clinical Sciences and Advanced Medicine,undefined
[7] Department of Pathobiology,undefined
[8] School of Veterinary Medicine,undefined
[9] University of Pennsylvania,undefined
[10] Penn Sarcoma Program,undefined
[11] Department of Orthopaedic Surgery,undefined
[12] Perelman School of Medicine,undefined
[13] University of Pennsylvania,undefined
来源
Cellular Oncology | 2022年 / 45卷
关键词
Soft-tissue sarcoma; DNA methylation; Canine; Nanaomycin A; Orthotopic; SLC29;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
页码:1277 / 1295
页数:18
相关论文
共 50 条
  • [1] Comparative oncology reveals DNMT3B as a molecular vulnerability in undifferentiated pleomorphic sarcoma
    Fuller, Ashley M.
    DeVine, Ann
    Murazzi, Ileana
    Mason, Nicola J.
    Weber, Kristy
    Eisinger-Mathason, T. S. Karin
    CELLULAR ONCOLOGY, 2022, 45 (06) : 1277 - 1295
  • [2] Structure of DNMT3B homo-oligomer reveals vulnerability to impairment by ICF mutations
    Linfeng Gao
    Yiran Guo
    Mahamaya Biswal
    Jiuwei Lu
    Jiekai Yin
    Jian Fang
    Xinyi Chen
    Zengyu Shao
    Mengjiang Huang
    Yinsheng Wang
    Gang Greg Wang
    Jikui Song
    Nature Communications, 13
  • [3] Structure of DNMT3B homo-oligomer reveals vulnerability to impairment by ICF mutations
    Gao, Linfeng
    Guo, Yiran
    Biswal, Mahamaya
    Lu, Jiuwei
    Yin, Jiekai
    Fang, Jian
    Chen, Xinyi
    Shao, Zengyu
    Huang, Mengjiang
    Wang, Yinsheng
    Wang, Gang Greg
    Song, Jikui
    NATURE COMMUNICATIONS, 2022, 13 (01)
  • [4] A novel DNMT3B subfamily, ΔDNMT3B, is the predominant form of DNMT3B in non-small cell lung cancer
    Wang, Luo
    Wang, Jie
    Sun, Shiyong
    Rodriguez, Marivonne
    Yue, Ping
    Jang, Se Jin
    Mao, Li
    INTERNATIONAL JOURNAL OF ONCOLOGY, 2006, 29 (01) : 201 - 207
  • [5] Molecular enzymology of the catalytic domains of the Dnmt3a and Dnmt3b DNA methyltransferases
    Gowher, H
    Jeltsch, A
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2002, 277 (23) : 20409 - 20414
  • [6] Modulation of Dnmt3b function in vitro by interactions with Dnmt3L, Dnmt3a and Dnmt3b splice variants
    Van Emburgh, Beth O.
    Robertson, Keith D.
    NUCLEIC ACIDS RESEARCH, 2011, 39 (12) : 4984 - 5002
  • [7] Methyltransferase DNMT3B in leukemia
    Zhang, Haibin
    Ying, Houqun
    Wang, Xiaozhong
    LEUKEMIA & LYMPHOMA, 2020, 61 (02) : 263 - 273
  • [8] Genomic profiling of DNA methyltransferases reveals a role for DNMT3B in genic methylation
    Baubec, Tuncay
    Colombo, Daniele F.
    Wirbelauer, Christiane
    Schmidt, Juliane
    Burger, Lukas
    Krebs, Arnaud R.
    Akalin, Altuna
    Schuebeler, Dirk
    NATURE, 2015, 520 (7546) : 243 - U278
  • [9] DNMT3B Expression Delays Leukemogenesis
    Tschanter, Petra
    Schulze, Isabell
    Baeumer, Nicole
    Surmann, Beate
    Agelopoulos, Konstantin
    Krug, Utz
    Berdel, Wolfgang E.
    Linhart, Heinz
    Mueller-Tidow, Carsten
    BLOOD, 2011, 118 (21) : 1473 - 1473
  • [10] Significance of DNMT3b in Oral Cancer
    Chen, Wen-Cheng
    Chen, Miao-Fen
    Lin, Paul-Yang
    PLOS ONE, 2014, 9 (03):