Angiogenesis inhibitors in gastric and gastroesophageal junction cancer

被引:0
|
作者
Giandomenico Roviello
Roberto Petrioli
Luigi Marano
Karol Polom
Daniele Marrelli
Armando Perrella
Franco Roviello
机构
[1] University of Siena,Medical Oncology Unit
[2] University of Siena,Unit of General and Minimally Invasive Surgery, Department of Medical, Surgical and Neuroscience
[3] University of Siena,Section of Advanced Surgical Oncology, Department of Medical, Surgical and Neurosciences
来源
Gastric Cancer | 2016年 / 19卷
关键词
Gastric cancer; VEGF; Bevacizumab; Ramucirumab;
D O I
暂无
中图分类号
学科分类号
摘要
Despite significant improvements in systemic chemotherapy during the past two decades, the prognosis of patients with advanced gastric and gastroesophageal junction adenocarcinoma remains poor. Because of molecular heterogeneity, it is essential to classify tumors based on the underlying oncogenic pathways and to develop targeted therapies acting on individual tumors. Unfortunately, although a number of molecular targets have been studied, very few of these agents can be used in a clinical setting. In this review, we summarize the available data on anti-angiogenic agents in advanced/metastatic gastric cancer.
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页码:31 / 41
页数:10
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