Systematic evaluation of CRISPR-Cas systems reveals design principles for genome editing in human cells

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作者
Yuanming Wang
Kaiwen Ivy Liu
Norfala-Aliah Binte Sutrisnoh
Harini Srinivasan
Junyi Zhang
Jia Li
Fan Zhang
Charles Richard John Lalith
Heyun Xing
Raghuvaran Shanmugam
Jia Nee Foo
Hwee Ting Yeo
Kean Hean Ooi
Tore Bleckwehl
Yi Yun Rachel Par
Shi Mun Lee
Nur Nadiah Binte Ismail
Nur Aidah Binti Sanwari
Si Ting Vanessa Lee
Jan Lew
Meng How Tan
机构
[1] School of Chemical and Biomedical Engineering,
[2] Nanyang Technological University,undefined
[3] Genome Institute of Singapore,undefined
[4] Agency for Science Technology and Research,undefined
[5] School of Biological Sciences,undefined
[6] Nanyang Technological University,undefined
[7] Lee Kong Chian School of Medicine,undefined
[8] Nanyang Technological University,undefined
[9] School of Applied Science,undefined
[10] Republic Polytechnic,undefined
[11] School of Life Sciences and Chemical Technology,undefined
[12] Ngee Ann Polytechnic,undefined
来源
Genome Biology | / 19卷
关键词
CRISPR; Genome editing; Non-homologous end joining (NHEJ); Homology-directed repair (HDR); Cas9 nucleases; Cpf1 nucleases;
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