Double-Blind Comparison of Escitalopram and Duloxetine in the Acute Treatment of Major Depressive Disorder

被引:0
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作者
Arif Khan
Anjana Bose
George S. Alexopoulos
Carl Gommoll
Dayong Li
Chetan Gandhi
机构
[1] Northwest Clinical Research Center,Department of Psychiatry and Behavioral Sciences
[2] Duke University School of Medicine,undefined
[3] Forest Research Institute,undefined
[4] Weill Medical College of Cornell University,undefined
来源
关键词
Major Depressive Disorder; Duloxetine; Escitalopram; Last Observation Carry Forward; MADRS Total Score;
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摘要
Background and objective: Escitalopram is the most selective serotonin reuptake inhibitor antidepressant; in contrast, duloxetine inhibits both serotonin and norepinephrine reuptake. Double-blind comparison studies may help guide treatment decisions by revealing the relative benefits of different therapeutic approaches. This study evaluated the efficacy and safety of escitalopram versus duloxetine in the acute treatment of patients with moderate to severe major depressive disorder.
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页码:481 / 492
页数:11
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