Intravenous 5-fluoro-2′-deoxycytidine administered with tetrahydrouridine increases the proportion of p16-expressing circulating tumor cells in patients with advanced solid tumors

被引：0
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作者：
Geraldine O.’Sullivan Coyne
Lihua Wang
Jennifer Zlott
Lamin Juwara
Joseph M. Covey
Jan H. Beumer
Mihaela C. Cristea
Edward M. Newman
Stephen Koehler
Jorge J. Nieva
Agustin A. Garcia
David R. Gandara
Brandon Miller
Sonny Khin
Sarah B. Miller
Seth M. Steinberg
Larry Rubinstein
Ralph E. Parchment
Robert J. Kinders
Richard L. Piekarz
Shivaani Kummar
Alice P. Chen
James H. Doroshow
机构：
[1] National Cancer Institute,Division of Cancer Treatment and Diagnosis
[2] Frederick National Laboratory for Cancer Research,Clinical Pharmacodynamic Biomarkers Program, Applied/Developmental Research Directorate
[3] Frederick National Laboratory for Cancer Research,Clinical Monitoring Research Program, Clinical Research Directorate
[4] University of Pittsburgh School of Pharmacy,Department of Pharmaceutical Sciences
[5] City of Hope National Medical Center,Department of Medical Oncology and Therapeutics Research
[6] City of Hope Medical Group,Center for Cancer Research
[7] University of Southern California Norris Comprehensive Cancer Center,undefined
[8] University of California Davis Cancer Center,undefined
[9] National Cancer Institute,undefined
[10] Louisiana State University,undefined
来源：
Cancer Chemotherapy and Pharmacology | 2020年 / 85卷
关键词：
DNMT1 inhibitors; Cancer epigenetics; Epigenetic modifying agents; Circulating tumor cells; p16;
D O I：
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学科分类号：
摘要：
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页码：979 / 993
页数：14
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    Rubinstein, Larry
    Parchment, Ralph E.
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    Piekarz, Richard L.
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    Doroshow, James H.
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