The role of ferroptosis in acute lung injury

被引：0
|
作者：
Xin Liu
Junqiang Zhang
Wang Xie
机构：
[1] BengBu Medical College,Department of Pulmonary and Critical Care Medicine, Division of Life Sciences and Medicine, The First Affiliated Hospital of USTC
[2] University of Science and Technology of China,undefined
来源：
Molecular and Cellular Biochemistry | 2022年 / 477卷
关键词：
Ferroptosis; Glutathione peroxidase 4; Lipid peroxidation; Acute lung injury;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Acute lung injury/acute respiratory distress syndrome (ALI/ARDS) is a common disease with high morbidity and mortality, and its pathogenesis is believed to be related to oxidative stress, apoptosis, inflammation, and hypoxia. Ferroptosis is a type of nonapoptotic cell death characterized by iron-dependent lipid peroxide accumulation and is involved in many cellular physiological processes. Recent studies have confirmed that ferroptosis may be involved in the development of ALI. This review summarizes the most recent discoveries on the role of ferroptosis in ALI to provide new strategies for its prevention and treatment.
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页码：1453 / 1461
页数：8
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