Polyfunctional imidazoles: XIII.1 Addition and cyclization reactions of 1-aryl-4-chloro-5-(2-nitroethenyl)-1H-imidazoles with sulfur and nitrogen nucleophiles

被引：0
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作者：
V. A. Chornous
O. Ya. Mel’nik
A. N. Grozav
S. Yu. Suikov
M. V. Vovk
机构：
[1] Bukovinian State Medical University,Institute of Organic Chemistry
[2] Ivano-Frankivsk National Medical University,undefined
[3] National Academy of Sciences of Ukraine,undefined
来源：
Russian Journal of Organic Chemistry | 2017年 / 53卷
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摘要：
1-Aryl-4-chloro-5-(2-nitroethenyl)-1H-imidazoles reacted with thiols and aromatic amines via Michael addition to give 5-[(1-arylsulfanyl)-2-nitroethyl)]-4-chloro-1H-imidazoles and N-[1-(1-aryl-4-chloro-1H-imidazol-5-yl)-2-nitroethyl]anilines, respectively. [2 + 3]-Cycloaddition of the title compounds to sodium azide afforded 4-(4-chloro-1H-imidazol-5-yl)-1H-1,2,3-triazoles.
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页码：407 / 412
页数：5
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