Protocol paper: a multi-center, double-blinded, randomized, 6-month, placebo-controlled study followed by 12-month open label extension to evaluate the safety and efficacy of Saracatinib in Fibrodysplasia Ossificans Progressiva (STOPFOP)

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作者
Bernard J. Smilde
Clemens Stockklausner
Richard Keen
Andrew Whittaker
Alex N. Bullock
Annette von Delft
Natasja M. van Schoor
Paul B. Yu
E. Marelise W. Eekhoff
机构
[1] Amsterdam UMC location Vrije Universiteit Amsterdam,Department of Internal Medicine Section Endocrinology
[2] Amsterdam Movement Sciences,Tissue Function and Regeneration
[3] Klinikum Garmisch-Partenkirchen,Department of Paediatrics
[4] Royal National Orthopaedic Hospital,Department of Rheumatology
[5] BioPharmaceuticals R&D,Emerging Innovations Unit, Discovery Sciences
[6] AstraZeneca,Centre for Medicines Discovery, Nuffield Department of Medicine
[7] University of Oxford,Oxford Biomedical Research Centre, National Institute for Health Research
[8] University of Oxford,Epidemiology and Data Science
[9] Amsterdam UMC location Vrije Universiteit Amsterdam,Aging and Later Life
[10] Amsterdam Public Health,Cardiovascular Research Center
[11] Massachusetts General Hospital,undefined
关键词
Fibrodysplasia Ossificans Progressiva; Saracatinib; AZD0530; Clinical trial; Drug repurposing; Drug repositioning;
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