A simple synthesis of 4-amino-6-methyl-1,1,1-trifluoro(trichloro)hepta-3,5-dien-2-ones and 2,2-dimethyl-6-trifluoromethyl-2,3-dihydro-4-pyridone

被引：0

作者：

V. Ya. Sosnovskikh

机构：

[1] A. M. Gor'ky Ural State University,

来源：

Russian Chemical Bulletin | 1997年 / 46卷

关键词：

aminodienones; β-diketones; dihydropyrones; ammonia; heterocyclization; 2,3-dihydro-2,2-dimethyl-6-trifluoromethyl-4-pyridone;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

Treatment of 2,2-dimethyl-6-trifluoro(trichloro)methyl-2,3-dihydro-4-pyrones with ammonia gives 4-amino-1,1,1-trifluoro(trichloro)-6-methylhepta-3,5-dien-2-ones. Under similar conditions 1,1,1-trifluoro-2-hydroxy-6-methylhepta-2,5-dien-4-one and 6-chloro-1, 1,1-trifluoro-2-hydroxy-6-methylhept-2-en-4-one cyclize into 2,2-dimethyl-6-trifluoromethyl-2,3-dihydro-4-pyridone.

引用

页码：2145 / 2146

页数：1

共 48 条

[1] A simple synthesis of 4-amino-6-methyl-1,1,1-trifluoro(trichloro)hepta-3,5-dien-2-ones and 2,2-dimethyl-6-trifluoromethyl-2,3-dihydro-4-pyridone
Sosnovskikh, VY
[J]. RUSSIAN CHEMICAL BULLETIN, 1997, 46 (12) : 2145 - 2146
[2] Reactions of regioisomeric 3,3-dimethyl- and 2,2-dimethyl-6-trifluoromethyl-2,3-dihydro-4-pyrones with N-nucleophiles
Sosnovskikh, VY
Mel'nikov, MY
[J]. RUSSIAN CHEMICAL BULLETIN, 1999, 48 (05) : 975 - 978
[3] Reactions of regioisomeric 3,3-dimethyl- and 2,2-dimethyl-6-trifluoromethyl-2,3-dihydro-4-pyrones with N-nucleophiles
V. Ya. Sosnovskikh
M. Yu. Mel'nikov
[J]. Russian Chemical Bulletin, 1999, 48 : 975 - 978
[4] Efficient synthesis of 2-aryl-6-methyl-2,3-dihydro-1H-pyridin-4-ones
Renault, O
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Rault, S
[J]. TETRAHEDRON LETTERS, 2000, 41 (05) : 681 - 683
[5] Cyclocondensation reaction of 4-aryl-4-methoxy-1,1,1-trifluoro-3-buten-2-ones with urea Synthesis of novel 6-aryl(5-methyl)-4-trifluoromethyl-2(1H)-pyrimidinones
Bonacorso, HG
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[J]. JOURNAL OF FLUORINE CHEMISTRY, 2003, 120 (01) : 29 - 32
[6] Synthesis of 4-(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-ylimino)-6-phenyl-1, 4-dihydro-2h-pyridazin-3-ones [2]
Rubtsov, A.E.
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[J]. Chemistry of Heterocyclic Compounds, 2003, 39 (04) : 541 - 542
[7] Synthesis and antimicrobial screening of 5-(4,7-dimethyl-2-oxo-2H-benzopyran-6-ylazo)-2-methyl-6-morpholin-4-yl-2,3dihydro-3H-pyrimidin-4-oneand5-(4,7dimethyl-2-oxo-2H-benzopyran-6-ylazo)2-methyl-6-piperidin-1-yl-2,3-dihydro-3H-pyrimidin-4-one
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[J]. INDIAN JOURNAL OF CHEMISTRY SECTION B-ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY, 2007, 46 (11): : 1873 - 1878
[8] Convenient synthesis and reactivity of ethyl 8-amino-6-methyl-2,3-dihydro-4H-1-benzopyran-2-carboxylate
Anderluh, M
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Dolenc, MS
[J]. SYNTHETIC COMMUNICATIONS, 2005, 35 (11) : 1461 - 1470
[9] Synthesis of 4-(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-ylimino)-6-phenyl-1,4-dihydro-2H-pyridazin-3-ones
Roubtsov, AE
Zalesov, VV
[J]. KHIMIYA GETEROTSIKLICHESKIKH SOEDINENII, 2003, (04): : 625 - 627
[10] AN EFFICIENT SYNTHESIS OF 6-(4-CHLOROPHENYL)-2,2-DIMETHYL-7-PHENYL-2,3-DIHYDRO-1H-PYRROLIZINE, A KEY INTERMEDIATE IN THE LICOFELONE SYNTHESIS
Radl, Stanislav
Stach, Jan
Cerny, Josef
Klecan, Ondrej
[J]. COLLECTION OF CZECHOSLOVAK CHEMICAL COMMUNICATIONS, 2009, 74 (06) : 1011 - 1022

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