Tendon injury: from biology to tendon repair

被引：0
|
作者：
Geoffroy Nourissat
Francis Berenbaum
Delphine Duprez
机构：
[1] Service de chirurgie orthopédique et traumatologique,
[2] INSERM UMR_S938,undefined
[3] DHU i2B,undefined
[4] Assistance Publique-Hopitaux de Paris,undefined
[5] Hôpital Saint-Antoine,undefined
[6] Service de rhumatologie,undefined
[7] INSERM UMR_S938,undefined
[8] DHU i2B,undefined
[9] Assistance Publique-Hopitaux de Paris,undefined
[10] Hôpital Saint-Antoine,undefined
[11] Centre national de la recherche scientifique UMR 7622,undefined
[12] IBPS Developmental Biology Laboratory,undefined
来源：
Nature Reviews Rheumatology | 2015年 / 11卷
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学科分类号：
摘要：
Tendon is a mechanosensitive tissueAbnormal loading leads to tendon injuriesMechanical forces are converted to biochemical signals that elicit cellular responses by tendon cellsSimilar mechanical and biological signals are involved in tendon development, homeostasis and repairA better understanding of the interaction between forces, intracellular pathways and gene transcription in the context of tendon biology is neededUnderstanding mechanobiology in tendon development, homeostasis and repair is critical to designing therapies for tendon injury
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页码：223 / 233
页数：10
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