RETRACTED ARTICLE: The exocyst in Candida albicans polarized secretion and filamentation

被引:0
|
作者
Alba A. Chavez-Dozal
Stella M. Bernardo
Samuel A. Lee
机构
[1] New Mexico VA Healthcare System,Section of Infectious Diseases
[2] University of New Mexico Health Science Center,Division of Infectious Diseases
来源
Current Genetics | 2016年 / 62卷
关键词
Exocyst; Filamentation; Polarisome; Secretion; Spitzenkörper;
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学科分类号
摘要
The exocyst is an octameric complex that orchestrates the docking and tethering of vesicles to the plasma membrane during exocytosis and is fundamental for key biological processes including growth and establishment of cell polarity. Although components of the exocyst are well conserved among fungi, the specific functions of each component of the exocyst complex unique to Candida albicans biology and pathogenesis are not fully understood. This commentary describes recent findings regarding the role of exocyst subunits Sec6 and Sec15 in C. albicans filamentation and virulence.
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页码:343 / 346
页数:3
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