Imaging of Fontan-associated liver disease

被引:0
|
作者
Jonathan R. Dillman
Andrew T. Trout
Tarek Alsaied
Anita Gupta
Adam M. Lubert
机构
[1] Cincinnati Children’s Hospital Medical Center,Department of Radiology
[2] University of Cincinnati College of Medicine,Department of Radiology
[3] University of Cincinnati College of Medicine,Department of Pediatrics
[4] Heart Institute,Department of Pathology
[5] Cincinnati Children’s Hospital Medical Center,undefined
[6] Cincinnati Children’s Hospital Medical Center,undefined
来源
Pediatric Radiology | 2020年 / 50卷
关键词
Children; Congestive hepatopathy; Fontan-associated liver disease; Fontan circulation; Liver; Magnetic resonance imaging; Single ventricle congenital heart disease; Ultrasound; Young adults;
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学科分类号
摘要
The Fontan operation has dramatically altered the natural history of functionally single ventricle congenital heart disease. Patients who have undergone the Fontan operation are living longer and, thus, noncardiac morbidity resulting from the Fontan operation is increasingly being recognized. Fontan-associated liver disease (FALD), one of the chief morbidities following the Fontan operation, is believed to be a multifactorial process that manifests as hepatic congestion and fibrosis, portal hypertension, and development of focal liver lesions, including malignant tumors. This article reviews the imaging findings of FALD in the pediatric and young adult population, reviews the literature related to the imaging of FALD and discusses possible screening algorithms for this population. The need for further research to better understand the causes of FALD, to establish if early liver stiffness measurements (or their change over time) predict long-term outcomes and complications, and to define optimal liver screening procedures is highlighted.
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页码:1528 / 1541
页数:13
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