APC/CFzr/Cdh1-dependent regulation of cell adhesion controls glial migration in the Drosophila PNS

被引:0
|
作者
Marion Silies
Christian Klämbt
机构
[1] Institut für Neurobiologie,
[2] Universität Münster,undefined
[3] Present address: Department of Neurobiology,undefined
[4] Stanford University,undefined
[5] Stanford,undefined
[6] California,undefined
[7] USA.,undefined
来源
Nature Neuroscience | 2010年 / 13卷
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摘要
For young glia to migrate along motor axons in the developing fly, their adhesion to the axon must be broken. Silies and Klämbt show that this is accomplished by removal of Fas2 from the axonal membrane, involving a ubiquitin ligase complex that has previously been implicated only in cell cycle regulation.
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页码:1357 / 1364
页数:7
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