β-site amyloid precursor protein-cleaving enzyme 1(BACE1) inhibitor treatment induces Aβ5-X peptides through alternative amyloid precursor protein cleavage

被引：0
|
作者：
Erik Portelius
Robert A Dean
Ulf Andreasson
Niklas Mattsson
Anni Westerlund
Maria Olsson
Ronald Bradley Demattos
Margaret M Racke
Henrik Zetterberg
Patrick C May
Kaj Blennow
机构：
[1] University of Gothenburg,Clinical Neurochemistry Laboratory, Institute of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry, The Sahlgrenska Academy
[2] Eli Lilly and Company,Lilly Research Laboratories
[3] University of California San Francisco,San Francisco VA Medical Center, Center for Imaging of Neurodegenerative Diseases (CIND)
[4] UCL Institute of Neurology,undefined
来源：
Alzheimer's Research & Therapy | / 6卷
关键词：
Amyloid Precursor Protein; Amyloid Precursor Protein Processing; BACE1 Inhibitor; Pharmacodynamic Marker; BACE1 Activity;
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