Anti-angiogenic, anti-inflammatory and anti-nociceptive activities of vanillyl alcohol

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作者
Hyun-Joo Jung
Yun Seon Song
Chang-Jin Lim
Eun-Hee Park
机构
[1] Kangwon National University,Division of Life Sciences and Research Institute of Life Sciences
[2] Sookmyung Women’s University,College of Pharmacy
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Vanillyl alcohol; Anti-inflammatory; Anti-angiogenic; Anti-nociceptive;
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摘要
Vanillyl alcohol displayed a significant inhibition in the chick chorioallantoic membrane (CAM) angiogenesis. Vanillyl alcohol was also shown to contain anti-inflammatory activity using acetic acid-induced permeability and carrageenan-induced air pouch models in mice. Anti-nociceptive activity of vanillyl alcohol was also assessed using acetic acid-induced writhing test in mice. Taken together, vanillyl alcohol possesses anti-angiogenic, anti-inflammatory, and anti-nociceptive activities, which may be partly responsible for pharmacological efficacies of several folkloric medicines containing vanillyl alcohol.
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页码:1275 / 1279
页数:4
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