Changes in Apoptosis and Cell Proliferation in Human Pineal Gland during Aging

被引：0
|
作者：
V. O. Polyakova
N. S. Linkova
S. A. Pichugin
机构：
[1] Saint-Petersburg Institute of Bioregulation and Gerontology,
[2] North-West Division,undefined
[3] Russian Academy of Medical Sciences,undefined
来源：
Bulletin of Experimental Biology and Medicine | 2011年 / 150卷
关键词：
pineal gland; aging; apoptosis; cell proliferation;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Immunohistochemical analysis of the expression of proapoptotic protein P53 and proliferation protein Ki-67 in human pineal gland showed that in people over 60 years pinealocyte proliferation is virtually absent. Moreover, pinealocyte apoptosis is more pronounced in elderly, whereas in senile and long-living individuals its intensity decreases.
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页码：468 / 470
页数：2
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