Study of a new group of bioregulators isolated from the greater plantain (Plantago major L.)

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作者
M. S. Krasnov
V. P. Yamskova
D. V. Margasyuk
O. G. Kulikova
A. P. Il’ina
E. Yu. Rybakova
I. A. Yamskov
机构
[1] Russian Academy of Sciences,Kol’tsov Institute of Developmental Biology
[2] Russian Academy of Sciences,Nesmeyanov Institute of Organoelement Compounds
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Apply Biochemistry; Frontal Research; Ultralow Dose; Wound Healing Effect; Pleurodeles Waltl;
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摘要
Proteins with physicochemical properties and biological activity similar to those of membranotropic homeostatic tissue-specific bioregulators that had been found earlier in various animal tissues were discovered in leaves of the common plantain (Plantago major L.). To study the specific activity of these plant proteins, we developed an experimental model for organotypic roller cultivation of newt (Pleurodeles waltl) skin tissue in vitro. We showed that the plant proteins of interest exert the wound-healing effect, which is characteristic of this plant, on the skin of vertebrates both in vitro and in vivo.
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页码:128 / 135
页数:7
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