New aspects of development of the cardiac conduction system, clinical relevance

被引:0
|
作者
Blom N.A. [1 ]
Poelmann R.E. [2 ]
DeRuiter M.C. [2 ]
Gittenberger-de Groot A.C. [2 ]
机构
[1] Dept. of Pediatric Cardiology, Leiden University Medical Center, Leiden
[2] Department of Anatomy and Embryology, Leiden University Medical Center, NL-2300 RC Leiden
来源
Herzschrittmachertherapie und Elektrophysiologie | 1999年 / 10卷 / 4期
关键词
Arrhythmia; Cardiac conduction system; Morphogenesis;
D O I
10.1007/s003990050066
中图分类号
学科分类号
摘要
Electrophysiological and new immunohistochemical markers have resulted in a better understanding of the development of the cardiac conduction system. In the primary heart tube the blood is pumped forward by peristaltic contractions as a result of alternating slow and fast conducting segments. At later stages a more specialized conduction system develops. The contribution of the primary fold and the sinus venosus to the formation of the cardiac conduction system is discussed as well as the role of extracardiac cells such as neural crest and epicardial derived cells. These new developmental aspects of the cardiac conduction system could provide an explanation of the position conduction system in heart malformations and certain arrhythmias in patients with structurally normal hearts.
引用
收藏
页码:201 / 207
页数:6
相关论文
共 50 条
  • [1] Development of the cardiac conduction system
    Mikawa, Takashi
    Hurtado, Romulo
    SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY, 2007, 18 (01) : 90 - 100
  • [2] Development of the Cardiac Conduction System
    Bhattacharyya, Samadrita
    Munshi, Nikhil V.
    COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY, 2020, 12 (12): : 1 - 21
  • [3] Development of the cardiac conduction system
    Moorman, AFM
    Christoffels, V
    JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY, 2004, 37 (01) : 368 - 368
  • [4] Development of the cardiac conduction system
    Moorman, AFM
    de Jong, F
    Denyn, MMFJ
    Lamers, WH
    CIRCULATION RESEARCH, 1998, 82 (06) : 629 - 644
  • [5] Cardiac Conduction System in Congenitally Corrected Transposition of the Great Arteries and Its Clinical Relevance
    Baruteau, Alban-Elouen
    Abrams, Dominic J.
    Ho, Siew Yen
    Thambo, Jean-Benoit
    McLeod, Christopher J.
    Shah, Maully J.
    JOURNAL OF THE AMERICAN HEART ASSOCIATION, 2017, 6 (12):
  • [6] Development of the cardiac conduction system in zebrafish
    Poon, Kar-Lai
    Liebling, Michael
    Kondrychyn, Igor
    Brand, Thomas
    Korzh, Vladimir
    GENE EXPRESSION PATTERNS, 2016, 21 (02) : 89 - 96
  • [7] Structure, function and clinical relevance of the cardiac conduction system, including the atrioventricular ring and outflow tract tissues
    Dobrzynski, Halina
    Anderson, Robert H.
    Atkinson, Andrew
    Borbas, Zoltan
    D'Souza, Alicia
    Fraser, John F.
    Inada, Shin
    Logantha, Sunil J. R. J.
    Monfredi, Oliver
    Morris, Gwilym M.
    Moorman, Anton F. M.
    Nikolaidou, Thodora
    Schneider, Heiko
    Szuts, Viktoria
    Temple, Ian P.
    Yanni, Joseph
    Boyett, Mark R.
    PHARMACOLOGY & THERAPEUTICS, 2013, 139 (02) : 260 - 288
  • [8] Molecular Regulation of Cardiac Conduction System Development
    Boulgakoff, Lucie
    D'Amato, Gaetano
    Miquerol, Lucile
    CURRENT CARDIOLOGY REPORTS, 2024, 26 (09) : 943 - 952
  • [9] The infrahisian conduction system and endocavitary cardiac structures: relevance for the invasive electrophysiologist
    Faisal F. Syed
    Jo Jo Hai
    Nirusha Lachman
    Christopher V. DeSimone
    Samuel J. Asirvatham
    Journal of Interventional Cardiac Electrophysiology, 2014, 39 : 45 - 56
  • [10] The infrahisian conduction system and endocavitary cardiac structures: relevance for the invasive electrophysiologist
    Syed, Faisal F.
    Hai, Jo Jo
    Lachman, Nirusha
    DeSimone, Christopher V.
    Asirvatham, Samuel J.
    JOURNAL OF INTERVENTIONAL CARDIAC ELECTROPHYSIOLOGY, 2014, 39 (01) : 45 - 56