New simple and one-pot synthetic routes to polyfunctionally substituted imidazo-[1,2-a]pyridines, pyrido[1,2-a]pyrimidines, pyrido[1,2-a]-1,3- diazepines, and imidazo[1,2-a]pyrimidines

被引：0
|
作者：
Hammouda M. [1 ]
Abou Zeid Z.M. [1 ]
Metwally M.A. [1 ]
机构：
[1] Department of Chemistry, Faculty of Science, University of Mansoura, Mansoura
来源：
Chemistry of Heterocyclic Compounds | 2005年 / 41卷 / 12期
关键词：
Arylidenemalononitriles; Mannich reaction; Nitroenamines;
D O I：
10.1007/s10593-006-0031-4
中图分类号：
学科分类号：
摘要：
Reactions of arylidenemalononitriles with 2-nitromethylene-substituted imidazolidine, hexahydropyrimidine, and hexahydro-1,3-diazepine afforded the title derivatives. Reaction of 2-nitromethylenehexahydropyrimidine with benzylamine or n-butylamine and formalin in a molar ratio of 1:1:2 gave the hexahydro-1H-imidazo[1,2-c]pyrimidine derivatives. Treatment of 2-nitromethyleneimidazolidine and hexahydropyrimidine with secondary aliphatic amines and formalin in a molar ratio of 1:1:1 afforded the corresponding methylene bis-compounds. ©2005 Springer Science+Business Media, Inc.
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页码：1525 / 1528
页数：3
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