Methylenetetrahydrofolate reductase (MTHFR) and breast cancer risk: a nested-case–control study and a pooled meta-analysis

被引：0
|
作者：
Tanja Langsenlehner
Wilfried Renner
Babak Yazdani-Biuki
Uwe Langsenlehner
机构：
[1] Medical University of Graz,Department of Therapeutic Radiology and Oncology
[2] Medical University of Graz,Clinical Institute of Medical and Laboratory Diagnostics
[3] Medical University of Graz,Deparment of Internal Medicine, Division of Rheumatology
[4] Medical University of Graz,Department of Internal Medicine, Division of Oncology
来源：
Breast Cancer Research and Treatment | 2008年 / 107卷
关键词：
Breast Cancer; Folate; Breast Cancer Risk; Premenopausal Woman; Breast Cancer Case;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Encouraged by recent studies on the MTHFR 677C>T polymorphism and breast cancer risk that suggested an association of the 677 TT genotype with increased breast cancer susceptibility in premenopausal women, we performed an analysis of the relationship between breast cancer risk and the MTHFR 677C>T polymorphism in 210 premenopausal breast cancer patients and sex- and agematched healthy control subjects. Our data show a trend for a higher MTHFR 677T allele frequency in breast cancer cases (61.9%) than in controls (51.5%, P = 0.082) supporting the results of previous studies.
引用
收藏
页码：459 / 460
页数：1
相关论文
共 50 条
  • [1] Methylenetetrahydrofolate reductase (MTHFR) and breast cancer risk: a nested-case-control study and a pooled meta-analysis
    Langsenlehner, Tanja
    Renner, Wilfried
    Yazdani-Biuki, Babak
    Langsenlehner, Uwe
    [J]. BREAST CANCER RESEARCH AND TREATMENT, 2008, 107 (03) : 459 - 460
  • [2] Methylenetetrahydrofolate reductase (MTHFR) and breast cancer risk: a nested-case-control study and a pooled meta-analysis
    Debora Macis
    Patrick Maisonneuve
    Harriet Johansson
    Bernardo Bonanni
    Edoardo Botteri
    Simona Iodice
    Barbara Santillo
    Silvana Penco
    Giacomo Gucciardo
    Giuseppe D’Aiuto
    Marco Rosselli del Turco
    Marinella Amadori
    Alberto Costa
    Andrea Decensi
    [J]. Breast Cancer Research and Treatment, 2007, 106 : 263 - 271
  • [3] Methylenetetrahydrofolate reductase (MTHFR) and breast cancer risk: A nested-case-control study and a pooled meta-analysis
    Macis, Debora
    Maisonneuve, Patrick
    Johansson, Harriet
    Bonanni, Bernardo
    Botteri, Edoardo
    Iodice, Simona
    Santillo, Barbara
    Penco, Silvana
    Gucciardo, Giacomo
    D'Aiuto, Giuseppe
    del Turco, Marco Rosselli
    Amadori, Marinella
    Costa, Alberto
    Decensi, Andrea
    [J]. BREAST CANCER RESEARCH AND TREATMENT, 2007, 106 (02) : 263 - 271
  • [4] Plasma folate, methylenetetrahydrofolate reductase (MTHFR), and colorectal cancer risk in three large nested case–control studies
    Jung Eun Lee
    Esther K. Wei
    Charles S. Fuchs
    David J. Hunter
    I-Min Lee
    Jacob Selhub
    Meir J. Stampfer
    Walter C. Willett
    Jing Ma
    Edward Giovannucci
    [J]. Cancer Causes & Control, 2012, 23 : 537 - 545
  • [5] Polymorphisms of methylenetetrahydrofolate reductase and the risk of prostate cancer:: a nested case-control study
    Van Guelpen, BR
    Wirén, SM
    Bergh, ARJ
    Hallmans, G
    Stattin, PE
    Hultdin, J
    [J]. EUROPEAN JOURNAL OF CANCER PREVENTION, 2006, 15 (01) : 46 - 50
  • [6] Methylenetetrahydrofolate reductase polymorphisms and breast cancer risk in Chinese population: a meta-analysis of 22 case-control studies
    Liang, Hongjie
    Yan, Yulan
    Li, Taijie
    Li, Ruolin
    Li, Meng
    Li, Shan
    Qin, Xue
    [J]. TUMOR BIOLOGY, 2014, 35 (02) : 1695 - 1701
  • [7] Polymorphisms of methylenetetrahydrofolate reductase and methionine synthase genes and bladder cancer risk: a case–control study with meta-analysis
    Meilin Wang
    Haixia Zhu
    Guangbo Fu
    Miaomiao Wang
    Zhizhong Zhang
    Qiang Lu
    Shizhi Wang
    Zhengdong Zhang
    [J]. Clinical and Experimental Medicine, 2009, 9
  • [8] Plasma folate, methylenetetrahydrofolate reductase (MTHFR), and colorectal cancer risk in three large nested case-control studies
    Lee, Jung Eun
    Wei, Esther K.
    Fuchs, Charles S.
    Hunter, David J.
    Lee, I-Min
    Selhub, Jacob
    Stampfer, Meir J.
    Willett, Walter C.
    Ma, Jing
    Giovannucci, Edward
    [J]. CANCER CAUSES & CONTROL, 2012, 23 (04) : 537 - 545
  • [9] Methylenetetrahydrofolate Reductase Gene Variant (MTHFR C677T) and Migraine: A Case Control Study and Meta-analysis
    Zainab Samaan
    Daria Gaysina
    Sarah Cohen-Woods
    Nick Craddock
    Lisa Jones
    Ania Korszun
    Mike Owen
    Andrew Mente
    Peter McGuffin
    Anne Farmer
    [J]. BMC Neurology, 11
  • [10] Methylenetetrahydrofolate Reductase Gene Variant (MTHFR C677T) and Migraine: A Case Control Study and Meta-analysis
    Samaan, Zainab
    Gaysina, Daria
    Cohen-Woods, Sarah
    Craddock, Nick
    Jones, Lisa
    Korszun, Ania
    Owen, Mike
    Mente, Andrew
    McGuffin, Peter
    Farmer, Anne
    [J]. BMC NEUROLOGY, 2011, 11
12345