Epigenetic regulation of satellite cell fate during skeletal muscle regeneration

被引：0
|
作者：
Jimmy Massenet
Edward Gardner
Bénédicte Chazaud
F. Jeffrey Dilworth
机构：
[1] Regenerative Medicine Program,Sprott Center for Stem Cell Research
[2] Ottawa Hospital Research Institute,Institut NeuroMyoGène
[3] Université Claude Bernard Lyon 1,Department of Cellular and Molecular Medicine
[4] CNRS 5310,LIFE Research Institute
[5] INSERM U1217,undefined
[6] 8 Rockefeller Ave,undefined
[7] University of Ottawa,undefined
[8] University of Ottawa,undefined
来源：
Skeletal Muscle | / 11卷
关键词：
Muscle stem cells; Regeneration; Epigenetics; Cell fate; Duchenne muscular dystrophy;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
In response to muscle injury, muscle stem cells integrate environmental cues in the damaged tissue to mediate regeneration. These environmental cues are tightly regulated to ensure expansion of muscle stem cell population to repair the damaged myofibers while allowing repopulation of the stem cell niche. These changes in muscle stem cell fate result from changes in gene expression that occur in response to cell signaling from the muscle environment.
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