The utility of cerebrospinal fluid analysis in patients with multiple sclerosis

被引:0
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作者
Martin Stangel
Sten Fredrikson
Edgar Meinl
Axel Petzold
Olaf Stüve
Hayrettin Tumani
机构
[1] Clinical Neuroimmunology and Neurochemistry,Department of Neurology
[2] Hannover Medical School,Division of Neurology, Department of Clinical Neuroscience
[3] Karolinska Institute,Department of Neurology and Neurotherapeutics
[4] Institute of Clinical Neuroimmunology,Department of Neurology
[5] Ludwig-Maximilian University,undefined
[6] VU University Medical Centre,undefined
[7] MS Centre Amsterdam,undefined
[8] The Netherlands and Institute of Neurology and Cerebrospinal Fluid and Immunology Unit,undefined
[9] University College London,undefined
[10] Queen Square,undefined
[11] Neurology Section,undefined
[12] Veterans Administration North Texas Health Care System,undefined
[13] Veterans Administration Medical Center,undefined
[14] University of Texas Southwestern Medical Center,undefined
[15] University Ulm,undefined
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摘要
Cerebrospinal fluid (CSF) investigation should be routinely performed in patients with a first clinical event that is suggestive of multiple sclerosis (MS). This Review highlights the value of existing CSF biomarkers in eliminating potential differential diagnoses for MS and understanding the underlying pathophysiology of this condition. The authors also discuss the potential for novel biomarkers that could be used in prognosis.
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页码:267 / 276
页数:9
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