Plasma neurofilament light chain and amyloid-β are associated with the kynurenine pathway metabolites in preclinical Alzheimer’s disease

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作者
Pratishtha Chatterjee
Henrik Zetterberg
Kathryn Goozee
Chai K. Lim
Kelly R. Jacobs
Nicholas J. Ashton
Abdul Hye
Steve Pedrini
Hamid R. Sohrabi
Tejal Shah
Prita R. Asih
Preeti Dave
Kaikai Shen
Kevin Taddei
David B. Lovejoy
Gilles J. Guillemin
Kaj Blennow
Ralph N. Martins
机构
[1] Macquarie University,Department of Biomedical Sciences
[2] Edith Cowan University,School of Medical Health and Sciences
[3] University of Gothenburg,Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology
[4] Sahlgrenska University Hospital,Clinical Neurochemistry Laboratory
[5] UCL Institute of Neurology,Department of Neurodegenerative Disease
[6] Queen Square,Clinical Research Department
[7] UK Dementia Research Institute at UCL,School of Psychiatry and Clinical Neurosciences
[8] KaRa Institute of Neurological Disease,Institute of Psychiatry, Psychology and Neuroscience, Maurice Wohl Institute Clinical Neuroscience Institute
[9] Sydney,NIHR Biomedical Research Centre for Mental Health and Biomedical Research Unit for Dementia
[10] Anglicare,Wallenberg Centre for Molecular and Translational Medicine
[11] Sydney,School of Medical and Health Sciences
[12] University of Western Australia,undefined
[13] King’s College London,undefined
[14] South London and Maudsley NHS Foundation,undefined
[15] University of Gothenburg,undefined
[16] Australian Alzheimer’s Research Foundation,undefined
[17] Australian eHealth Research Centre,undefined
[18] CSIRO,undefined
[19] The Cooperative Research Centre for Mental Health,undefined
[20] Edith Cowan University,undefined
[21] Ralph & Patricia Sarich Neuroscience Research Institute,undefined
关键词
Blood markers; Neuroinflammation; Neurodegeneration; Alzheimer’s disease; Neurofilament light chain; Amyloid-beta; Kynurenine pathway; Brain amyloid-beta; Blood amyloid-beta;
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