Preclinical and clinical activity of DZD1516, a full blood–brain barrier-penetrant, highly selective HER2 inhibitor

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作者
Jian Zhang
Nicholas P. McAndrew
Xiaojia Wang
Yiqun Du
Brian DiCarlo
Mei Wang
Kan Chen
Wenlei Yu
Xichun Hu
机构
[1] Fudan University Shanghai Cancer Center,Phase I Clinical Trial Center
[2] Fudan University,Department of Oncology, Shanghai Medical College
[3] UCLA David Geffen School of Medicine,Division of Hematology/Oncology
[4] Zhejiang Cancer Hospital,Department of Medical Oncology
[5] Dizal Pharmaceutical,undefined
[6] Fudan University Shanghai Cancer Center,undefined
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HER2; Tyrosine kinase inhibitor; Blood–brain barrier; Breast cancer; Central nervous system metastases;
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