Research progress on the pathogenesis of diabetic retinopathy

被引:0
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作者
Hongbo Li
Xinyu Liu
Hua Zhong
Jiani Fang
Xiaonan Li
Rui Shi
Qi Yu
机构
[1] Xi’an Medical University,School of Basic Medical Sciences
[2] Shaanxi Provincial People’s Hospital,Department of Ophthalmology
[3] Xi’an Medical University,Institute of Basic and Translational Medicine
来源
关键词
Diabetic retinopathy; Oxidative stress; Inflammatory reaction; Mitochondrial disorders; Gene epigenetic inheritance; Hemoglobin; Intestinal flora; Amino acid metabolism;
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摘要
Diabetic retinopathy is one of the most common and serious microvascular complications of diabetes mellitus. There are many factors leading to diabetic retinopathy, and its pathogenesis is still unclear. At present, there are still no effective measures for the early treatment of diabetic retinopathy, and the treatment options available when diabetes progresses to advanced stages are very limited, and the treatment results are often unsatisfactory. Detailed studies on the molecular mechanisms of diabetic retinopathy pathogenesis and the development of new therapeutic agents are of great importance. This review describes the potential pathogenesis of diabetic retinopathy for experimental studies and clinical practice.
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