The Role of Oxazolidinones in l-Proline-Assisted Aldol-Type Reactions

被引：0
|
作者：
Ivan A. Konstantinov
Linda J. Broadbelt
机构：
[1] Northwestern University,Department of Chemical and Biological Engineering
来源：
Topics in Catalysis | 2010年 / 53卷
关键词：
Oxazolidinones; -proline; Aldol reactions; DFT;
D O I：
暂无
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学科分类号：
摘要：
In this study, the formation of oxazolidinone intermediates along the reaction coordinates of two l-proline-catalyzed reactions was investigated using high-level quantum mechanical calculations. Our results suggest that the final product is produced via routes other than the currently-adopted catalytic cycle for l-proline, including routes where oxazolidinones are directly involved.
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页码：1031 / 1038
页数：7
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