Nasopharyngeal carcinoma metastasis to the pituitary gland: A case report and literature review

被引:0
|
作者
Brandon Gunn G. [1 ,6 ]
Villa R.D. [2 ]
Sedler R.R. [3 ]
Hardwicke F. [4 ]
Fornari G.A. [1 ]
Mark R.J. [5 ]
机构
[1] Texas Tech Univ. Health Sci. Center, School of Medicine, Southwest Cancer Center, Lubbock, TX
[2] Department of Internal Medicine, Texas Tech Medical Center, University Medical Center, Lubbock, TX
[3] Department of Neurosurgery, Texas Tech Medical Center, University Medical Center, Lubbock, TX
[4] Department of Hematology/Oncology, Texas Tech Medical Center, University Medical Center, Lubbock, TX
[5] Department of Radiation Oncology, Texas Tech Medical Center, University Medical Center, Lubbock, TX
[6] Lubbock, TX 79411
关键词
Autologous stem cell transplant; Central nervous system; Epstein-Barr virus; In-situ hybridization; Metastasis; Nasopharyngeal carcinoma; Pituitary gland;
D O I
10.1023/B:NEON.0000024750.93572.ce
中图分类号
学科分类号
摘要
While nasopharyngeal carcinoma (NPC) commonly invades the skull base, true central nervous system metastasis is a rare phenomenon. We report a case of NPC metastasis to the pituitary gland and review the literature for similar events. Eight months after his definitive radiation therapy, our patient presented with symptoms of optic chiasm compression and panhypopituitarism. Medical imaging revealed a pituitary mass but demonstrated no evidence of skull base erosion or direct intracranial extension. Subsequent biopsy of the pituitary lesion was confirmed as NPC in origin with Epstein-Barr virus-encoded RNA in-situ hybridization studies. The patient was treated with high dose chemotherapy followed by autologous stem cell transplant, which produced short-term symptomatic relief and at least a 7 month survival. © 2004 Kluwer Academic Publishers.
引用
收藏
页码:87 / 90
页数:3
相关论文
共 50 条
  • [1] Nasopharyngeal carcinoma metastasis to the pituitary gland: a case report and literature review
    Gunn, GB
    Villa, RD
    Sedler, RR
    Hardwicke, F
    Fornari, GA
    Mark, RJ
    [J]. JOURNAL OF NEURO-ONCOLOGY, 2004, 68 (01) : 87 - 90
  • [2] Parotid Gland Metastasis of Nasopharyngeal Carcinoma: Case Report and Review of the Literature
    Dong, X. R.
    Zhang, T.
    Fan, L.
    Zhang, S.
    Wu, G.
    [J]. JOURNAL OF INTERNATIONAL MEDICAL RESEARCH, 2009, 37 (06) : 1994 - 1999
  • [3] Hepatocellular carcinoma metastasis in the pituitary gland: case report and review of the literature
    M.V. Karamouzis
    M. Melachrinou
    M. Fratzoglou
    Ch. Labropoulou-Karatza
    H.P. Kalofonos
    [J]. Journal of Neuro-Oncology, 2003, 63 : 173 - 177
  • [4] Hepatocellular carcinoma metastasis in the pituitary gland: case report and review of the literature
    Karamouzis, MV
    Melachrinou, M
    Fratzoglou, M
    Labropoulou-Karatza, C
    Kalofonos, HP
    [J]. JOURNAL OF NEURO-ONCOLOGY, 2003, 63 (02) : 173 - 177
  • [5] Pituitary metastasis of salivary gland carcinoma mimicking hypophysitis: A case report and literature review
    Tsutsui, Takeyoshi
    Hayashi, Kosuke
    Oda, Masashi
    Kada, Shinpei
    Yamazoe, Naohiro
    Saiki, Masaaki
    [J]. INTERNATIONAL JOURNAL OF SURGERY CASE REPORTS, 2023, 109
  • [6] Brain Metastasis of Nasopharyngeal Carcinoma: A Case Report and Literature Review
    Kaidar-Person, Orit
    Kuten, Jonathan
    Atrash, Fadi
    Billan, Salem
    Kuten, Abraham
    [J]. CASE REPORTS IN MEDICINE, 2012, 2012
  • [7] Undifferentiated carcinoma of the pituitary gland: A case report and review of the literature
    Lee, Hsun-Hwa
    Hung, Shih-Han
    Tseng, Te-Ming
    Lin, Yun-Ho
    Cheng, Ju-Chuan
    [J]. ONCOLOGY LETTERS, 2014, 7 (03) : 778 - 780
  • [8] Nasopharyngeal carcinoma metastasis to the mammary gland: A case report
    Li, Shuang
    Yang, Jiyuan
    [J]. ONCOLOGY LETTERS, 2015, 9 (01) : 275 - 277
  • [9] Nasopharyngeal Metastasis from Breast Carcinoma: A Case Report and a Review of the Literature
    Sellami, Moncef
    Kallel, Souha
    Ben Ayed, Mariam
    Mellouli, Manel
    Boudawara, Tahya Sellami
    Mnejja, Malek
    Hammami, Bouthaina
    Achour, Imen
    Charfeddine, Ilhem
    [J]. ENT-EAR NOSE & THROAT JOURNAL, 2022,
  • [10] Breast metastasis from nasopharyngeal carcinoma: A case report and review of the literature
    Leach, Ben I.
    Sun, Bonnie
    Petrovic, Lydia
    Liu, Stephen V.
    [J]. ONCOLOGY LETTERS, 2013, 5 (06) : 1859 - 1861