Fifty Tumor Necrosis Factor–Based Isolated Limb Perfusions for Limb Salvage in Patients Older Than 75 Years With Limb-Threatening Soft Tissue Sarcomas and Other Extremity Tumors

被引：0
|
作者：
Boudewijn van Etten
Albertus N. van Geel
Johannes H. W. de Wilt
Alexander M. M. Eggermont
机构：
[1] University Hospital Rotterdam-Daniel den Hoed Cancer Center,Department of Surgical Oncology
[2] University Hospital Rotterdam-Daniel den Hoed Cancer Center,Department of Surgical Oncology
来源：
Annals of Surgical Oncology | 2003年 / 10卷
关键词：
Melanoma; Tumor Necrosis Factor; Melphalan; Soft Tissue Sarcoma; Total Series;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Background: Isolated limb perfusion (ILP) with tumor necrosis factor (TNF) and melphalan is highly effective in treating limb-threatening soft tissue sarcoma (STS) and other bulky tumors. Because of fear of TNF-associated toxicity, ILP with TNF is not offered to older patients in some cancer centers, although especially in older patients, every attempt to avoid an amputation that may end their independence must be considered.
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页码：32 / 37
页数：5
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