Pharmacotherapy can be useful in treating peripheral arterial disease, but options are limited

Effective pharmacological options for peripheral arterial disease are limited. For intermittent claudication that persists despite exercise training, cilostazol is the first-line therapy and pentoxifylline is a second-line option, while the agents potentially useful for critical limb ischaemia when revascularization is unsuitable include cilostazol and prostaglandins. Cardiovascular risk factors should be modified in all patients. © 2013 Springer International Publishing Switzerland.