The history of Toll-like receptors — redefining innate immunity

被引:0
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作者
Luke A. J. O'Neill
Douglas Golenbock
Andrew G. Bowie
机构
[1] Luke A. J. O'Neill and Andrew G. Bowie are at the School of Biochemistry and Immunology,Douglas Golenbock is at the Division of Infectious Diseases & Immunology
[2] Trinity Biomedical Sciences Institute,undefined
[3] Trinity College Dublin,undefined
[4] Dublin 2,undefined
[5] Ireland.,undefined
[6] University of Massachusetts Medical School,undefined
[7] Plantation Street,undefined
[8] Worcester,undefined
[9] MA 01605,undefined
[10] USA.,undefined
来源
Nature Reviews Immunology | 2013年 / 13卷
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摘要
The past 15 years have seen a breakthrough in the field of innate immunity. In this Timeline article, the authors discuss the early events that led to the identification of Toll-like receptors as the prototype pattern-recognition receptors that link innate and adaptive immune responses.
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页码:453 / 460
页数:7
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