Direct dorsal hippocampal–prelimbic cortex connections strengthen fear memories

被引：0
|
作者：
Xiaojing Ye
Dana Kapeller-Libermann
Alessio Travaglia
M Carmen Inda
Cristina M Alberini
机构：
[1] Center for Neural Science,
[2] New York University,undefined
[3] Present address: Natural Sciences Department,undefined
[4] Hostos Community College,undefined
[5] City University of New York,undefined
[6] Bronx,undefined
[7] New York,undefined
[8] USA.,undefined
来源：
Nature Neuroscience | 2017年 / 20卷
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学科分类号：
摘要：
The authors show that a direct pathway from the dorsal hippocampus to the prelimbic cortex is necessary for contextual fear memory strengthening. Molecular analyses and functional targeting revealed that prelimbic excitatory and inhibitory synapses have a critical role in promoting memory strengthening, while inhibiting extinction.
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页码：52 / 61
页数：9
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