Photodynamic immunotherapy of cancers based on nanotechnology: recent advances and future challenges

被引：0

作者：

Zhaoyuan Liu

Zhongjian Xie

Wenting Li

Xinqiang Wu

Xiaofeng Jiang

Guanhua Li

Liangqi Cao

Dawei Zhang

Qiwen Wang

Ping Xue

Han Zhang

机构：

[1] The Second Affiliated Hospital of Guangzhou Medical University,Department of Hepatobiliary Surgery

[2] The Second Affiliated Hospital of Guangzhou Medical University,Department of Traditional Chinese Medicine

[3] Shenzhen University,Key Laboratory of Optoelectronic Devices and Systems of Ministry of Education and Guangdong Province, Collaborative Innovation Centre for Optoelectronic Science & Technology, Institute of Microscale Optoelectronics

[4] Shenzhen University,College of Physics and Optoelectronic Engineering

[5] Shenzhen University,Shenzhen Key Laboratory of Micro

[6] Sun Yat-Sen University,Nano Photonic Information Technology, Guangdong Laboratory of Artificial Intelligence and Digital Economy (SZ)

来源：

Journal of Nanobiotechnology | / 19卷

关键词：

Photodynamic therapy; Nanotechnology; Immunotherapy; Cancer treatment;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

Photodynamic therapy (PDT) is a non-invasive or minimally-invasive treatment which applies photosensitizers (PSs) to create reactive oxygen species (ROS) exposed to light trigger to destroy cancer cells. PDT can activate host anti-tumor immune responses but not powerful enough to kill metastatic tumors. Because of its carrier advantage, imaging, and therapeutic function together with enhanced permeability and retention (EPR) effect, nano-materials have already been used in photo-immunotherapy. Herein, photodynamic immunotherapy (PDIT) based on nanotechnology seems to be a hopeful new form of cancer therapy. In this article, we firstly summarize the recent development in photodynamic immunotherapy based on nanotechnology.

引用

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