Molecular Docking Studies, Antiproliferative Evaluation, and Synthesis of 7-(1H-Indol-3-yl)pyrido[2,3-d]pyrimidine Derivatives

被引：0
|
作者：
M. A. Radwan
O. Al Rugaie
W. Al Abdulmonem
H. Awad
E. Zayed
机构：
[1] Department of Chemistry,
[2] Collage of Science,undefined
[3] Qassim University,undefined
[4] Applied Organic Chemistry Department,undefined
[5] National Research Center,undefined
[6] Department of Basic Medical Sciences,undefined
[7] Unaizah College of Medicine and Medical Sciences,undefined
[8] Qassim University,undefined
[9] Department of Pathology,undefined
[10] College of Medicine,undefined
[11] Qassim University,undefined
[12] Tanning Materials and Leather Technology Department,undefined
[13] National Research Centre,undefined
[14] Green Chemistry Department,undefined
[15] National Research Centre,undefined
来源：
Russian Journal of Bioorganic Chemistry | 2022年 / 48卷
关键词：
MCF-7; HepG-2; antitumor; indole; pyridopyrimidine; molecular docking;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
页码：809 / 820
页数：11
相关论文
共 50 条
  • [1] Molecular Docking Studies, Antiproliferative Evaluation, and Synthesis of 7-(1H-Indol-3-yl)pyrido[2,3-d]pyrimidine Derivatives
    Radwan, M. A.
    Al Rugaie, O.
    Al Abdulmonem, W.
    Awad, H.
    Zayed, E.
    RUSSIAN JOURNAL OF BIOORGANIC CHEMISTRY, 2022, 48 (04) : 809 - 820
  • [2] Studies on synthesis of novel pyrido[2,3-d]pyrimidine derivatives, evaluation of their antimicrobial activity and molecular docking
    Veeraswamy, B.
    Madhu, D.
    Dev, G. Jitender
    Poornachandra, Y.
    Kumar, G. Shravan
    Kumar, C. Ganesh
    Narsaiah, B.
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2018, 28 (09) : 1670 - 1675
  • [3] Exploring the Antiproliferative Potency of Pyrido[2,3-d]Pyrimidine Derivatives: Studies on Design, Synthesis, Anticancer Evaluation, SAR, Docking, and DFT Calculations
    Abd-Alsalam, Eman
    Hafez, Hend N.
    Assay, Mohamed G.
    Ali, Ali Khalil
    El-Farargy, Ahmed F.
    Abbass, Eslam M.
    CHEMISTRY & BIODIVERSITY, 2024, 21 (02)
  • [4] Synthesis, Pharmacological Evaluation and Molecular Docking Studies of N-[2-(1H-indol-3-yl)Acetyl]Arylsulfonohydrazides
    K. Rubab
    M. A. Abbasi
    S. Z. Aziz-ur-Rehman
    S. A. A. Siddiqui
    M. Shah
    M. A. Ashraf
    F. A. Qurat-ul-Ain
    M. Lodhi
    Hina Khan
    I. Shahid
    Pharmaceutical Chemistry Journal, 2021, 55 : 665 - 678
  • [5] SYNTHESIS OF SOME PYRIDO[2,3-D]PYRIMIDINE AND PYRIDO[3,2-D]PYRIMIDINE DERIVATIVES
    SOLODUCHO, J
    ARCHIV DER PHARMAZIE, 1990, 323 (08) : 513 - 515
  • [6] Synthesis, Pharmacological Evaluation and Molecular Docking Studies of N-[2-(1H-indol-3-yl)Acetyl]Arylsulfonohydrazides
    Rubab, K.
    Abbasi, M. A.
    Aziz-ur-Rehman
    Siddiqui, S. Z.
    Shah, S. A. A.
    Ashraf, M.
    Qurat-ul-Ain
    Lodhi, M. A.
    Khan, F. A.
    Shahid, M.
    Fatima, Hina
    Ahmad, I
    PHARMACEUTICAL CHEMISTRY JOURNAL, 2021, 55 (07) : 665 - 678
  • [7] 3D-QSAR and Docking Studies of Pyrido[2,3-d]pyrimidine Derivatives as Wee1 Inhibitors
    Zeng, Guo-hua
    Wu, Wen-juan
    Zhang, Rong
    Sun, Jun
    Xie, Wen-guo
    Shen, Yong
    CHINESE JOURNAL OF CHEMICAL PHYSICS, 2012, 25 (03) : 297 - 307
  • [8] SYNTHESIS OF INDOLYL DERIVATIVES OF PYRIDO[2,3-D]PYRIMIDINE
    STUPNIKOVA, TV
    NUZHNAYA, TV
    KLYUYEV, NA
    CHERVINSKII, AY
    KHIMIYA GETEROTSIKLICHESKIKH SOEDINENII, 1983, (01): : 115 - 118
  • [9] Synthesis and anticancer evaluation of diaryl pyrido[2,3-d]pyrimidine /alkyl substituted pyrido[2,3-d]pyrimidine derivatives as thymidylate synthase inhibitors
    Kumar, Adarsh
    Backer, Nabeel
    Paliwal, Harshali
    Singh, Ankit Kumar
    Debbaraman, Tanushree
    Singh, Vikramjeet
    Kumar, Pradeep
    BMC CHEMISTRY, 2024, 18 (01)
  • [10] TiO2 Nanoparticles Catalyzed Synthesis, Pharmacological Evaluation, and Molecular Docking Studies of New Pyrido[2,3-d]Pyrimidine Derivatives as CDK1 Inhibitors
    Alsalam, Eman Abd
    Awad, Hanem M.
    Abbass, Eslam M.
    Hafez, Hend N.
    Assy, Mohamed G.
    Ali, Ali Khalil
    El Farargy, Ahmed F.
    Fathalla, Maher
    CHEMISTRY AFRICA-A JOURNAL OF THE TUNISIAN CHEMICAL SOCIETY, 2025,
12345